Product Name
SEMA3C, Polyclonal Antibody
Full Product Name
SEMA3C, CT (SEMA3C, SEMAE, Semaphorin-3C, Semaphorin-E)
Product Synonym Names
Anti -SEMA3C, CT (SEMA3C, SEMAE, Semaphorin-3C, Semaphorin-E)
Product Gene Name
anti-SEMA3C antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
Chromosome: 7; NC_000007.13 (80371854..80551695, complement). Location: 7q21-q31
3D Structure
ModBase 3D Structure for Q99985
Species Reactivity
Human, Mouse
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Immunogen
SEMA3C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 600-630 amino acids from the C-terminal region of human SEMA3C.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Other Notes
Small volumes of anti-SEMA3C antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-SEMA3C antibody
SEMA3C may be involved in diverse cell survival mechanisms.
Product Categories/Family for anti-SEMA3C antibody
Antibodies; Abs to Plexin, Semaphorin
Applications Tested/Suitable for anti-SEMA3C antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-SEMA3C antibody
Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
NCBI/Uniprot data below describe general gene information for SEMA3C. It may not necessarily be applicable to this product.
NCBI Accession #
NP_006370.1
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NCBI GenBank Nucleotide #
NM_006379.3
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UniProt Primary Accession #
Q99985
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UniProt Related Accession #
Q99985[Other Products]
Molecular Weight
85,207 Da[Similar Products]
NCBI Official Full Name
semaphorin-3C
NCBI Official Synonym Full Names
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
NCBI Official Symbol
SEMA3C [Similar Products]
NCBI Official Synonym Symbols
SemE; SEMAE
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NCBI Protein Information
semaphorin-3C; sema E; semaphorin E; semaphorin-E
UniProt Protein Name
Semaphorin-3C
UniProt Synonym Protein Names
Semaphorin-E
Protein Family
Semaphorin
UniProt Gene Name
SEMA3C [Similar Products]
UniProt Synonym Gene Names
SEMAE; Sema E [Similar Products]
UniProt Entry Name
SEM3C_HUMAN
UniProt Comments for SEMA3C
SEMA3C: a secreted protein that may be involved in cell survival mechanisms. Expressed intensely in the heart, skeletal muscle, colon, small intestine, ovary, testis, and prostate. Faint expression ubiquitously among other organs, including brain. Binds with high affinity to the receptor NRP2.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 7q21-q31
Cellular Component: extracellular space; membrane
Molecular Function: receptor activity; semaphorin receptor binding
Biological Process: neural tube development; response to drug; axon guidance; limb bud formation; somitogenesis; immune response; blood vessel remodeling; neural crest cell migration; post-embryonic development
Research Articles on SEMA3C
1. Capillary-like tubular formation was reduced by the addition of culture media of sema3C miRNA cells.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
