Product Name
Amelogenin, X isoform (Amelx), Recombinant Protein
Full Product Name
Recombinant Rat Amelogenin, X isoform (Amelx)
Product Gene Name
Amelx recombinant protein
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
17-210aa, Full Length of Mature Protein
Sequence
MPLPPHPGSP GYINLSYEKS HSQAINTDRT ALVLTPLKWY QSMIRQPYPS YGYEPMGGWL HHQIIPVLSQ QHPPSHTLQP HHHLPVVPAQ QPVAPQQPMM PVPGHHSMTP TQHHQPNIPP SAQQPFQQPF QPQAIPPQSH QPMQPQSPLH PMQPLAPQPP LPPLFSMQPL SPILPELPLE AWPATDKTKR EEVD
3D Structure
ModBase 3D Structure for P63278
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Amelx recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
Amelx recombinant protein
This gene encodes a member of the amelogenin family of extracellular matrix proteins. Amelogenins are involved in biomineralization during tooth enamel development. Mutations in this gene cause X-linked amelogenesis imperfecta. Alternative splicing results in multiple transcript variants encoding different isoforms.
NCBI/Uniprot data below describe general gene information for Amelx. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001258002.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001271073.1
[Other Products]
UniProt Primary Accession #
P63278
[Other Products]
UniProt Secondary Accession #
P45559; Q62945; Q63640; Q78E56[Other Products]
UniProt Related Accession #
P63278[Other Products]
Molecular Weight
21,868 Da
NCBI Official Full Name
amelogenin, X isoform isoform 2
NCBI Official Synonym Full Names
amelogenin, X-linked
NCBI Official Symbol
Amelx [Similar Products]
NCBI Official Synonym Symbols
Amel; LRAP
[Similar Products]
NCBI Protein Information
amelogenin, X isoform
UniProt Protein Name
Amelogenin, X isoform
UniProt Synonym Protein Names
Leucine-rich amelogenin peptide; LRAP
Protein Family
Amelogenin
UniProt Gene Name
Amelx [Similar Products]
UniProt Synonym Gene Names
Amel; Amgx; LRAP [Similar Products]
NCBI Summary for Amelx
may play a role in mineralization of tooth enamel matrix [RGD, Feb 2006]
UniProt Comments for Amelx
Plays a role in the biomineralization of teeth. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel.
Research Articles on Amelx
1. The aim of this study was to verify the expression, distribution and role of Rho GTPases in ameloblasts and odontoblasts during tooth development in correlation with actin and tubulin arrangements and amelogenin and dentin sialophosphoprotein expression.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.