Product Name
Peroxin 14 (PEX14), Polyclonal Antibody
Full Product Name
Peroxin 14 Polyclonal Antibody
Product Gene Name
anti-PEX14 antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for O75381
Other Notes
Small volumes of anti-PEX14 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for PEX14. It may not necessarily be applicable to this product.
NCBI Accession #
NP_004556.1
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NCBI GenBank Nucleotide #
NM_004565.2
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UniProt Primary Accession #
O75381
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UniProt Secondary Accession #
Q8WX51; B2R7N1; B3KML6; B7Z1N2[Other Products]
UniProt Related Accession #
O75381[Other Products]
Molecular Weight
36,702 Da[Similar Products]
NCBI Official Full Name
peroxisomal membrane protein PEX14
NCBI Official Synonym Full Names
peroxisomal biogenesis factor 14
NCBI Official Symbol
PEX14 [Similar Products]
NCBI Official Synonym Symbols
NAPP2; PBD13A; Pex14p; dJ734G22.2
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NCBI Protein Information
peroxisomal membrane protein PEX14
UniProt Protein Name
Peroxisomal membrane protein PEX14
UniProt Synonym Protein Names
PTS1 receptor-docking protein; Peroxin-14; Peroxisomal membrane anchor protein PEX14
Protein Family
Peroxisomal membrane protein
UniProt Gene Name
PEX14 [Similar Products]
NCBI Summary for PEX14
This gene encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C-terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in this gene results in one form of Zellweger syndrome. [provided by RefSeq, Jul 2008]
UniProt Comments for PEX14
Peroxisome membrane protein that is an essential component of the peroxisomal import machinery. Functions as a docking factor for the predominantly cytoplasmic PTS1 receptor (PEX5). Plays a key role for peroxisome movement through a direct interaction with tubulin.
Research Articles on PEX14
1. Data suggest that soluble/cytosolic PEX5 interacts with PEX14/PEX13 complex, a model for the docking/translocation module (DTM) of the peroxisomal matrix protein translocon; PEX14/PEX13 complex appears to function in peroxisomal membrane as large cavity into which cytosolic PEX5 can enter to release its cargo. (PEX = peroxisomal biogenesis factor)
Precautions
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Disclaimer
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