Product Name
gephyrin (GPHN), ELISA Kit
Full Product Name
Mouse Gephyrin [Includes: Molybdopterin adenylyltransferase, GPHN ELISA Kit
Product Synonym Names
Mouse Gephyrin [Includes: Molybdopterin adenylyltransferase (GPHN) ELISA kit; GEPH; GPH; GPHRYN; KIAA1385; ; gephyrin
Product Gene Name
GPHN elisa kit
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
Request Current Manual
3D Structure
ModBase 3D Structure for Q8BUV3
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of GPHN elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for GPHN purchase
MBS9322352 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the gephyrin (GPHN) ELISA Kit target analytes in
biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing GPHN. The ELISA analytical biochemical technique of the MBS9322352 kit is based on GPHN antibody-GPHN antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect GPHN antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, GPHN. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
NCBI/Uniprot data below describe general gene information for GPHN. It may not necessarily be applicable to this product.
NCBI Accession #
NP_766540.2
[Other Products]
NCBI GenBank Nucleotide #
NM_172952.3
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UniProt Primary Accession #
Q8BUV3
[Other Products]
UniProt Secondary Accession #
E9QKJ1[Other Products]
UniProt Related Accession #
Q8BUV3[Other Products]
Molecular Weight
83,282 Da
NCBI Official Full Name
gephyrin isoform 2
NCBI Official Synonym Full Names
gephyrin
NCBI Official Symbol
Gphn [Similar Products]
NCBI Official Synonym Symbols
GPH; geph; GPHRYN; AI662856; BC027112; C230040D23; 5730552E08Rik
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NCBI Protein Information
gephyrin
UniProt Protein Name
Gephyrin
UniProt Synonym Protein Names
Domain G
UniProt Gene Name
Gphn [Similar Products]
UniProt Synonym Gene Names
MPT adenylyltransferase; MPT Mo-transferase [Similar Products]
UniProt Entry Name
GEPH_MOUSE
UniProt Comments for GPHN
gephyrin: Microtubule-associated protein involved in membrane protein-cytoskeleton interactions. It is thought to anchor the inhibitory glycine receptor (GLYR) to subsynaptic microtubules. Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. Homotrimer. Interacts with GABARAP. Inhibited by copper and tungsten. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 2.10.1.1; Adaptor/scaffold; EC 2.7.7.75
Cellular Component: extrinsic to plasma membrane; postsynaptic membrane; cytoskeleton; membrane; cytoplasm; plasma membrane; synapse; intracellular; cell junction
Molecular Function: transferase activity; protein binding; protein homodimerization activity; metal ion binding; cytoskeletal protein binding; nucleotide binding; protein complex scaffold; catalytic activity; ATP binding; receptor binding
Biological Process: establishment of protein localization; molybdenum incorporation into molybdenum-molybdopterin complex; metabolic process; Mo-molybdopterin cofactor biosynthetic process; establishment of synaptic specificity at neuromuscular junction; molybdopterin cofactor biosynthetic process; protein homooligomerization
Research Articles on GPHN
1. these findings suggest that gephyrin may be a key factor in BDNF-dependent GABAAR regulation in the amygdala.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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