Full Product Name
GPHN Antibody, FITC conjugated
Product Synonym Names
Gephyrin; Domain G; Molybdopterin molybdenumtransferase; GPHN
Product Gene Name
anti-GPHN antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q9NQX3
Purity/Purification
>95%, Protein G purified
Immunogen
Recombinant Human Gephyrin protein (360-460AA)
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-GPHN antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-GPHN antibody
Microtubule-associated protein involved in membrane protein-cytoskeleton interactions. It is thought to anchor the inhibitory glycine receptor (GLYR) to subsynaptic microtubules. Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.
Product Categories/Family for anti-GPHN antibody
Neuroscience
Applications Tested/Suitable for anti-GPHN antibody
ELISA (EIA)
NCBI/Uniprot data below describe general gene information for GPHN. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001019389.1
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NCBI GenBank Nucleotide #
NM_001024218.1
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UniProt Primary Accession #
Q9NQX3
[Other Products]
UniProt Secondary Accession #
Q96KU4; Q9H4E9; Q9P2G2[Other Products]
UniProt Related Accession #
Q9NQX3[Other Products]
Molecular Weight
83,448 Da
NCBI Official Full Name
gephyrin isoform 2
NCBI Official Synonym Full Names
gephyrin
NCBI Official Symbol
GPHN [Similar Products]
NCBI Official Synonym Symbols
GPH; GEPH; HKPX1; GPHRYN; MOCODC
[Similar Products]
NCBI Protein Information
gephyrin
UniProt Protein Name
Gephyrin
UniProt Synonym Protein Names
Domain E
UniProt Gene Name
GPHN [Similar Products]
UniProt Synonym Gene Names
MPT Mo-transferase [Similar Products]
NCBI Summary for GPHN
This gene encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described; however, the full-length nature of all transcript variants is not currently known. [provided by RefSeq, Jul 2008]
UniProt Comments for GPHN
Microtubule-associated protein involved in membrane protein-cytoskeleton interactions. It is thought to anchor the inhibitory glycine receptor (GLYR) to subsynaptic microtubules. Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.
Research Articles on GPHN
1. these data reveal that IQSEC3 acts together with gephyrin to regulate inhibitory synapse development.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
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