Full Product Name
Anti-AMPD1 Antibody
Product Gene Name
anti-AMPD1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P23109
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Affinity Purification
Concentration
1mg/ml (lot specific)
Immunogen
A synthetic peptide of human AMPD1
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Other Notes
Small volumes of anti-AMPD1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-AMPD1 antibody
Adenosine monophosphate deaminase 1 catalyzes the deamination of AMP to IMP in skeletal muscle and plays an important role in the purine nucleotide cycle.
Applications Tested/Suitable for anti-AMPD1 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-AMPD1 antibody
WB: 1:500-1:2000
IHC: 1:50-1:200
NCBI/Uniprot data below describe general gene information for AMPD1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000027.2
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NCBI GenBank Nucleotide #
NM_000036.2
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UniProt Primary Accession #
P23109
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UniProt Secondary Accession #
Q5TF00; Q5TF02; A8K5N4; B2RAM1; F2Z3B3[Other Products]
UniProt Related Accession #
P23109[Other Products]
Molecular Weight
89,763 Da
NCBI Official Full Name
AMP deaminase 1 isoform 1
NCBI Official Synonym Full Names
adenosine monophosphate deaminase 1
NCBI Official Symbol
AMPD1 [Similar Products]
NCBI Official Synonym Symbols
MAD; MADA; MMDD
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NCBI Protein Information
AMP deaminase 1
UniProt Protein Name
AMP deaminase 1
UniProt Synonym Protein Names
AMP deaminase isoform M; Myoadenylate deaminase
Protein Family
AMP deaminase
UniProt Gene Name
AMPD1 [Similar Products]
NCBI Summary for AMPD1
Adenosine monophosphate deaminase 1 catalyzes the deamination of AMP to IMP in skeletal muscle and plays an important role in the purine nucleotide cycle. Two other genes have been identified, AMPD2 and AMPD3, for the liver- and erythocyte-specific isoforms, respectively. Deficiency of the muscle-specific enzyme is apparently a common cause of exercise-induced myopathy and probably the most common cause of metabolic myopathy in the human. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010]
UniProt Comments for AMPD1
AMP deaminase plays a critical role in energy metabolism.CautionIt is uncertain whether Met-1 or Met-34 is the initiator.
Research Articles on AMPD1
1. T allele of AMPD1 gene C34T polymorphism may be correlated with LVEF, LVEDD and SBP, which plays a protective role in the cardiac functions and blood pressure in cardiovascular disease patients.
Precautions
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Disclaimer
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