Product Name
PDCD1LG2, cDNA Clone
Full Product Name
PDCD1LG2 cDNA Clone
Product Gene Name
PDCD1LG2 cdna clone
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atgatcttcc tcctgctaat gttgagcctg gaattgcagc ttcaccagat agcagcttta ttcacagtga cagtccctaa ggaactgtac ataatagagc atggcagcaa tgtgaccctg gaatgcaact ttgacactgg aagtcatgtg aaccttggag caataacagc cagtttgcaa aaggtggaaa atgatacatc cccacaccgt gaaagagcca ctttgctgga ggagcagctg cccctaggga aggcctcgtt ccacatacct caagtccaag tgagggacga aggacagtac caatgcataa tcatctatgg ggtcgcctgg gactacaagt acctgactct gaaagtcaaa gcttcctaca ggaaaataaa cactcacatc ctaaaggttc cagaaacaga tgaggtagag ctcacctgcc aggctacagg ttatcctctg gcagaagtat cctggccaaa cgtcagcgtt cctgccaaca ccagccactc caggacccct gaaggcctct accaggtcac cagtgttctg cgcctaaagc caccccctgg cagaaacttc agctgtgtgt tctggaatac tcacgtgagg gaacttactt tggccagcat tgaccttcaa agtcagatgg aacccaggac ccatccaact tggctgcttc acattttcat cccctcctgc atcattgctt tcattttcat agccacagtg atagccctaa gaaaacaact ctgtcaaaag ctgtattctt caaaagacac aacaaaaaga cctgtcacca caacaaagag ggaagtgaac agtgctatct ga
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of PDCD1LG2 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for PDCD1LG2. It may not necessarily be applicable to this product.
NCBI Accession #
BC113678
[Other Products]
UniProt Secondary Accession #
Q14CN8; Q5T7Z6; Q6JXL8; Q6JXL9[Other Products]
UniProt Related Accession #
Q9BQ51[Other Products]
Molecular Weight
20,745 Da
NCBI Official Full Name
Homo sapiens programmed cell death 1 ligand 2, mRNA
NCBI Official Synonym Full Names
programmed cell death 1 ligand 2
NCBI Official Symbol
PDCD1LG2 [Similar Products]
NCBI Official Synonym Symbols
B7DC; Btdc; PDL2; CD273; PD-L2; PDCD1L2; bA574F11.2
[Similar Products]
NCBI Protein Information
programmed cell death 1 ligand 2
UniProt Protein Name
Programmed cell death 1 ligand 2
UniProt Synonym Protein Names
Butyrophilin B7-DC; B7-DC; CD_antigen: CD273
Protein Family
Programmed cell death
UniProt Gene Name
PDCD1LG2 [Similar Products]
UniProt Synonym Gene Names
B7DC; CD273; PDCD1L2; PDL2; PD-1 ligand 2; PD-L2; PDCD1 ligand 2; Programmed death ligand 2; B7-DC [Similar Products]
UniProt Entry Name
PD1L2_HUMAN
UniProt Comments for PDCD1LG2
PDCD1LG2: Involved in the costimulatory signal, essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. Belongs to the immunoglobulin superfamily. BTN/MOG family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Receptor, misc.
Chromosomal Location of Human Ortholog: 9p24.2
Cellular Component: plasma membrane
Biological Process: negative regulation of activated T cell proliferation; negative regulation of interferon-gamma production; negative regulation of interleukin-10 production; T cell costimulation
Research Articles on PDCD1LG2
1. PD-L2 expression was neither associated with VEGF-TKI responsiveness nor patients' outcome
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
