Product Name
IGHMBP2, Polyclonal Antibody
Full Product Name
Anti-IGHMBP2 Antibody
Product Gene Name
anti-IGHMBP2 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Affinity Purification
Concentration
1mg/ml (lot specific)
Immunogen
Recombinant protein of human IGHMBP2
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Other Notes
Small volumes of anti-IGHMBP2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-IGHMBP2 antibody
This gene encodes a helicase superfamily member that binds a specific DNA sequence from the immunoglobulin mu chain switch region. Mutations in this gene lead to spinal muscle atrophy with respiratory distress type 1.
Applications Tested/Suitable for anti-IGHMBP2 antibody
Western Blot (WB)
Application Notes for anti-IGHMBP2 antibody
WB: 1:500-1:2000
NCBI/Uniprot data below describe general gene information for IGHMBP2. It may not necessarily be applicable to this product.
NCBI Accession #
AAH25299.1
[Other Products]
UniProt Secondary Accession #
Q00443; Q14177; A0PJD2[Other Products]
UniProt Related Accession #
P38935[Other Products]
Molecular Weight
109,149 Da
NCBI Official Full Name
IGHMBP2 protein, partial
NCBI Official Synonym Full Names
immunoglobulin mu DNA binding protein 2
NCBI Official Symbol
IGHMBP2 [Similar Products]
NCBI Official Synonym Symbols
HCSA; HMN6; CATF1; CMT2S; SMARD1; SMUBP2; ZFAND7
[Similar Products]
NCBI Protein Information
DNA-binding protein SMUBP-2
UniProt Protein Name
DNA-binding protein SMUBP-2
UniProt Synonym Protein Names
ATP-dependent helicase IGHMBP2; Glial factor 1; GF-1; Immunoglobulin mu-binding protein 2
Protein Family
DNA-binding protein
UniProt Gene Name
IGHMBP2 [Similar Products]
UniProt Synonym Gene Names
SMBP2; SMUBP2; GF-1 [Similar Products]
NCBI Summary for IGHMBP2
This gene encodes a helicase superfamily member that binds a specific DNA sequence from the immunoglobulin mu chain switch region. Mutations in this gene lead to spinal muscle atrophy with respiratory distress type 1. [provided by RefSeq, Jul 2008]
UniProt Comments for IGHMBP2
5' to 3' helicase that unwinds RNA and DNA duplices in an ATP-dependent reaction. Acts as a transcription regulator. Required for the transcriptional activation of the flounder liver-type antifreeze protein gene. Exhibits strong binding specificity to the enhancer element B of the flounder antifreeze protein gene intron. Binds to the insulin II gene RIPE3B enhancer region. May be involved in translation (). DNA-binding protein specific to 5'-phosphorylated single-stranded guanine-rich sequence related to the immunoglobulin mu chain switch region. Preferentially binds to the 5'-GGGCT-3' motif. Interacts with tRNA-Tyr. Stimulates the transcription of the human neurotropic virus JCV.
Research Articles on IGHMBP2
1. A, c.2356delG, c.2597_2598delAG and c.1061-2A > G, are reported for the first time">detected IGHMBP2 mutations in a cohort of Chinese Charcot-Marie-Tooth disease type 2 patients; four mutations, c.1489G > A, c.2356delG, c.2597_2598delAG and c.1061-2A > G, are reported for the first time
Precautions
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Disclaimer
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