Product Name
actin, alpha, cardiac muscle 1 (ACTC1), Polyclonal Antibody
Full Product Name
Rabbit anti-human actin, alpha, cardiac muscle 1 polyclonal Antibody
Product Synonym Names
actin; alpha; cardiac muscle 1; ACTC1; ACTC; CMD1R; CMH11
Product Gene Name
anti-ACTC1 antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Storage Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-ACTC1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-ACTC1 antibody
ELISA (EIA), Western Blot (WB)
NCBI/Uniprot data below describe general gene information for ACTC1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_005150.1
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NCBI GenBank Nucleotide #
NM_005159.4
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UniProt Secondary Accession #
P04270[Other Products]
UniProt Related Accession #
P68032[Other Products]
Molecular Weight
42,019 Da[Similar Products]
NCBI Official Full Name
actin, alpha cardiac muscle 1 proprotein
NCBI Official Synonym Full Names
actin, alpha, cardiac muscle 1
NCBI Official Symbol
ACTC1 [Similar Products]
NCBI Official Synonym Symbols
ACTC; ASD5; CMD1R; CMH11; LVNC4
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NCBI Protein Information
actin, alpha cardiac muscle 1
UniProt Protein Name
Actin, alpha cardiac muscle 1
UniProt Synonym Protein Names
Alpha-cardiac actin
UniProt Gene Name
ACTC1 [Similar Products]
UniProt Synonym Gene Names
ACTC [Similar Products]
UniProt Entry Name
ACTC_HUMAN
NCBI Summary for ACTC1
Actins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC). [provided by RefSeq, Jul 2008]
UniProt Comments for ACTC1
ACTC1: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Belongs to the actin family.
Protein type: Motility/polarity/chemotaxis; Myosin-binding; Contractile; Cell development/differentiation; Cytoskeletal
Chromosomal Location of Human Ortholog: 15q14
Cellular Component: I band; extracellular space; sarcomere; focal adhesion; membrane; cytoplasm; actin filament; cytosol
Molecular Function: myosin binding; ATPase activity; ATP binding
Biological Process: response to drug; apoptosis; actin filament-based movement; muscle thin filament assembly; metabolic process; actomyosin structure organization and biogenesis; cardiac myofibril assembly; muscle filament sliding; response to ethanol; heart contraction; cardiac muscle morphogensis; actin-myosin filament sliding; cardiac muscle contraction; negative regulation of apoptosis
Disease: Cardiomyopathy, Familial Hypertrophic, 11; Atrial Septal Defect 5; Cardiomyopathy, Dilated, 1r
Research Articles on ACTC1
1. Genetic variations at the ACTC1 gene may contribute to progression to chronic Chagas Cardiomyopathy
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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