Full Product Name
GDAP1 antibody - middle region
Product Gene Name
anti-GDAP1 antibody
[Similar Products]
Product Synonym Gene Name
CMTRIA; CMT4; CMT4A[Similar Products]
Antibody/Peptide Pairs
GDAP1 peptide (MBS3241112) is used for blocking the activity of GDAP1 antibody (MBS3216212)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Synthetic peptide located within the following region: IPAYATTRIR SQIGNTESEL KKLAEENPDL QEAYIAKQKR LKSKLLDHDN
3D Structure
ModBase 3D Structure for Q8TB36
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 92%
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-GDAP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-GDAP1 antibody
This is a rabbit polyclonal antibody against GDAP1. It was validated on Western Blot
Target Description: This gene encodes a member of the ganglioside-induced differentiation-associated protein family, which may play a role in a signal transduction pathway during neuronal development. Mutations in this gene have been associated with various forms of Charcot-Marie-Tooth Disease and neuropathy. Two transcript variants encoding different isoforms have been identified for this gene.
Product Categories/Family for anti-GDAP1 antibody
Polyclonal; Developmental Biology; Signal Transduction; Disease Related;
Applications Tested/Suitable for anti-GDAP1 antibody
Western Blot (WB)
Western Blot (WB) of anti-GDAP1 antibody
WB Suggested Anti-GDAP1 Antibody
Titration: 1.0 ug/ml
Positive Control: ACHN Whole Cell
NCBI/Uniprot data below describe general gene information for GDAP1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_061845
[Other Products]
NCBI GenBank Nucleotide #
NM_018972
[Other Products]
UniProt Primary Accession #
Q8TB36
[Other Products]
UniProt Related Accession #
Q8TB36[Other Products]
NCBI Official Full Name
ganglioside-induced differentiation-associated protein 1 isoform a
NCBI Official Synonym Full Names
ganglioside induced differentiation associated protein 1
NCBI Official Symbol
GDAP1 [Similar Products]
NCBI Official Synonym Symbols
CMT4; CMT4A; CMTRIA
[Similar Products]
NCBI Protein Information
ganglioside-induced differentiation-associated protein 1
UniProt Protein Name
Ganglioside-induced differentiation-associated protein 1
Protein Family
Ganglioside-induced differentiation-associated protein
UniProt Gene Name
GDAP1 [Similar Products]
UniProt Synonym Gene Names
GDAP1 [Similar Products]
UniProt Entry Name
GDAP1_HUMAN
NCBI Summary for GDAP1
This gene encodes a member of the ganglioside-induced differentiation-associated protein family, which may play a role in a signal transduction pathway during neuronal development. Mutations in this gene have been associated with various forms of Charcot-Marie-Tooth Disease and neuropathy. Two transcript variants encoding different isoforms and a noncoding variant have been identified for this gene. [provided by RefSeq, Feb 2012]
Research Articles on GDAP1
1. G mutation (p.Y124C) expands the mutation spectrum of GDAP1 gene, but further study is needed to clarify the underlying pathogenesis.">The mutation of GDAP1 gene may be related to the pathogenesis of autosomal dominant AD-CMT in this pedigree. The newly discovered c.371A>G mutation (p.Y124C) expands the mutation spectrum of GDAP1 gene, but further study is needed to clarify the underlying pathogenesis.
Precautions
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Disclaimer
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