Full Product Name
GDAP1 Rabbit Polyclonal
Product Gene Name
anti-GDAP1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Species Reactivity
Human, Mouse
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Immunogen
Ganglioside-induced differentiation-associated protein 1
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-GDAP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-GDAP1 antibody
ELISA (EIA), Western Blot (WB)
NCBI/Uniprot data below describe general gene information for GDAP1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_061845.2
[Other Products]
NCBI GenBank Nucleotide #
NM_018972.2
[Other Products]
UniProt Secondary Accession #
A8K957; E7FJF3; E7FJF4[Other Products]
UniProt Related Accession #
Q8TB36[Other Products]
Molecular Weight
33,480 Da
NCBI Official Full Name
ganglioside-induced differentiation-associated protein 1 isoform a
NCBI Official Synonym Full Names
ganglioside induced differentiation associated protein 1
NCBI Official Symbol
GDAP1 [Similar Products]
NCBI Official Synonym Symbols
CMT4; CMT4A; CMTRIA
[Similar Products]
NCBI Protein Information
ganglioside-induced differentiation-associated protein 1
UniProt Protein Name
Ganglioside-induced differentiation-associated protein 1
Protein Family
Ganglioside-induced differentiation-associated protein
UniProt Gene Name
GDAP1 [Similar Products]
UniProt Synonym Gene Names
GDAP1 [Similar Products]
UniProt Entry Name
GDAP1_HUMAN
NCBI Summary for GDAP1
This gene encodes a member of the ganglioside-induced differentiation-associated protein family, which may play a role in a signal transduction pathway during neuronal development. Mutations in this gene have been associated with various forms of Charcot-Marie-Tooth Disease and neuropathy. Two transcript variants encoding different isoforms and a noncoding variant have been identified for this gene. [provided by RefSeq, Feb 2012]
UniProt Comments for GDAP1
GDAP1: the ganglioside-induced differentiation associated protein-1 gene causes autosomal recessive demyelinating or axonal Charcot-Marie-Tooth neuropathy (CMT).
Protein type: Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 8q21.11
Cellular Component: cytoplasm; integral to mitochondrial outer membrane; membrane; mitochondrion; nucleus
Molecular Function: glutathione transferase activity
Biological Process: glutathione metabolic process; mitochondrial fission; mitochondrial fusion; protein targeting to mitochondrion; response to retinoic acid
Disease: Charcot-marie-tooth Disease, Axonal, Type 2k; Charcot-marie-tooth Disease, Axonal, With Vocal Cord Paresis, Autosomal Recessive; Charcot-marie-tooth Disease, Recessive Intermediate A; Charcot-marie-tooth Disease, Type 4a
Research Articles on GDAP1
1. study reports on 2 Charcot-Marie-Tooth (CMT) families in which a newly identified Glu222Lys mutation within the GDAP1 gene segregates both in autosomal dominant and recessive traits
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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