Product Name
SRGAP3, cDNA Clone
Full Product Name
SRGAP3 cDNA Clone
Product Gene Name
SRGAP3 cdna clone
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atgaacaatg tcatcgtccg cctctcccag atcagtgagg atgtcatcag actcttcaaa aagagcaagg agattggcct gcagatgcac gaggagctcc tgaaggtgac caatgagctc tacacagtca tgaaaaccta ccacatgtac catgcagaga gcatcagtgc ggaaagcaag ctgaaggagg ctgagaagca ggaggagaag cagttcaata agtcaggaga cctcagcatg aacctgctcc ggcacgagga ccggccccag cgccgcagct ctgtgaagaa gattgagaag atgaaggaga agaggcaggc caagtactct gagaacaagc tgaaatgcac aaaggcccgg aatgactact tgctcaatct ggcagccacc aacgcagcta taagcaaata ctacatccat gatgtctctg atctgatcga ttgctgtgat ttgggcttcc atgccagcct ggcccgcacc ttccggacct atctctcagc tgaatacaac ctggagacct ctcgccacga agggctggat gtcattgaga atgcagtgga caacctggat tcccgaagtg acaagcacac agtcatggac atgtgcaatc aagtcttctg ccctccactc aagttcgagt tccagcccca catgggggat gaggtctgcc aggtcagcgc tcagcagccc gtccagacag aactgctcat gcgttatcac cagctgcagt ccagactggc caccctcaag atagagaatg aggaggttag gaaaaccctg gatgccacca tgcagacatt acaggacatg ctgactgtgg aggactttga tgtctccgat gccttccaac acagtcgatc gacagagtcc gtcaagtcgg ctgcctctga ggcctacatg agcaagatca acattgccaa gaggagagcc aaccagcagg aaacagaaat gttttatttt acaaacgggc ctgatgatgt tttccccatt tgccatccaa gactctga
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of SRGAP3 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for SRGAP3. It may not necessarily be applicable to this product.
NCBI Accession #
BC039300
[Other Products]
UniProt Secondary Accession #
Q8IX13; Q8IZV8[Other Products]
UniProt Related Accession #
O43295[Other Products]
Molecular Weight
57,227 Da
NCBI Official Full Name
Homo sapiens SLIT-ROBO Rho GTPase activating protein 3, mRNA
NCBI Official Synonym Full Names
SLIT-ROBO Rho GTPase activating protein 3
NCBI Official Symbol
SRGAP3 [Similar Products]
NCBI Official Synonym Symbols
WRP; MEGAP; SRGAP2; ARHGAP14
[Similar Products]
NCBI Protein Information
SLIT-ROBO Rho GTPase-activating protein 3
UniProt Protein Name
SLIT-ROBO Rho GTPase-activating protein 3
UniProt Synonym Protein Names
Mental disorder-associated GAP; Rho GTPase-activating protein 14; WAVE-associated Rac GTPase-activating protein; WRP
Protein Family
SLIT-ROBO Rho GTPase-activating protein
UniProt Gene Name
SRGAP3 [Similar Products]
UniProt Synonym Gene Names
ARHGAP14; KIAA0411; KIAA1156; MEGAP; SRGAP2; srGAP3; WRP [Similar Products]
UniProt Entry Name
SRGP3_HUMAN
UniProt Comments for SRGAP3
ARHGAP14: GTPase-activating protein for RAC1 and perhaps Cdc42, but not for RhoA small GTPase. May attenuate RAC1 signaling in neurons. A chromosomal aberration involving SRGAP3 is found in a patient with severe idiopathic mental retardation. Translocation t(X;3)(p11.2;p25). 3 isoforms of the human protein are produced by alternative splicing.
Protein type: GAPs, Rac/Rho; GAPs
Chromosomal Location of Human Ortholog: 3p25.3
Cellular Component: cytoplasm; cytosol
Molecular Function: GTPase activator activity; protein binding; Rac GTPase binding
Biological Process: negative regulation of cell migration; regulation of small GTPase mediated signal transduction
Research Articles on SRGAP3
1. A single PXXP motif in the C-terminal region of srGAP3 mediates binding to multiple SH3 domains.
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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