Product Name
B3GNT6, Polyclonal Antibody
Full Product Name
B3GNT6 Antibody, HRP conjugated
Product Synonym Names
Acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1; 3-N-acetylglucosaminyltransferase; Core 3 synthase; UDP-GlcNAc:betaGal beta-1; 3-N-acetylglucosaminyltransferase 6; BGnT-6; Beta-1; 3-Gn-T6; Beta-1; 3-N-acetylglucosaminyltransferase 6; Beta3Gn-T6; B3GNT6
Product Gene Name
anti-B3GNT6 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q6ZMB0
Purity/Purification
>95%, Protein G purified
Immunogen
Recombinant Human Acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1, 3-N-acetylglucosaminyltransferase protein (251-345AA)
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-B3GNT6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-B3GNT6 antibody
Beta-1, 3-N-acetylglucosaminyltransferase that synthesizes the core 3 structure of the O-glycan, an important precursor in the biosynthesis of mucin-type glycoproteins. Plays an important role in the synthesis of mucin-type O-glycans in digestive organs.
Product Categories/Family for anti-B3GNT6 antibody
Metabolism; Signal transduction
Applications Tested/Suitable for anti-B3GNT6 antibody
ELISA (EIA)
NCBI/Uniprot data below describe general gene information for B3GNT6. It may not necessarily be applicable to this product.
NCBI Accession #
NP_619651.3
[Other Products]
NCBI GenBank Nucleotide #
NM_138706.4
[Other Products]
UniProt Primary Accession #
Q6ZMB0
[Other Products]
UniProt Secondary Accession #
Q6ZSC5; Q8TAZ4; Q8TDX1; E9PKS1[Other Products]
UniProt Related Accession #
Q6ZMB0[Other Products]
Molecular Weight
42,785 Da
NCBI Official Full Name
acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase
NCBI Official Synonym Full Names
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6
NCBI Official Symbol
B3GNT6 [Similar Products]
NCBI Official Synonym Symbols
BGnT-6; B3Gn-T6; beta3Gn-T6; beta-1,3-Gn-T6
[Similar Products]
NCBI Protein Information
acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase
UniProt Protein Name
Acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase
UniProt Synonym Protein Names
Core 3 synthase; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6; BGnT-6; Beta-1,3-Gn-T6; Beta-1,3-N-acetylglucosaminyltransferase 6; Beta3Gn-T6
Protein Family
Acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase
UniProt Gene Name
B3GNT6 [Similar Products]
UniProt Synonym Gene Names
BGnT-6; Beta-1,3-Gn-T6; Beta-1,3-N-acetylglucosaminyltransferase 6; Beta3Gn-T6 [Similar Products]
NCBI Summary for B3GNT6
The protein encoded by this gene is a beta-1,3-N-acetylglucosaminyltransferase that adds an N-acetylglucosamine moiety to N-acetylgalactosamine-modified serine or threonine. The encoded enzyme is responsible for creating the core 3 structure of O-glycans, which are important components of mucin-type glycoproteins. [provided by RefSeq, Dec 2016]
UniProt Comments for B3GNT6
Beta-1,3-N-acetylglucosaminyltransferase that synthesizes the core 3 structure of the O-glycan, an important precursor in the biosynthesis of mucin-type glycoproteins. Plays an important role in the synthesis of mucin-type O-glycans in digestive organs.
Research Articles on B3GNT6
1. alpha2beta1 integrin acquired core3 O-glycans in cells expressing core3 synthase with decreased maturation of beta1 integrin, leading to decreased levels of the alpha2beta1 integrin complex
Precautions
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Disclaimer
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