Glutamate receptor ionotropic, NMDA 2A, Polyclonal Antibody

Glutamate [NMDA] receptor subunit epsilon-1; N-methyl D-aspartate receptor subtype 2A; GRIN2A; NMDAR2A

For Research Use Only. Not for use in diagnostic procedures.

Polyclonal

Rabbit

The antibody detects endogenous level of total Glutamate receptor ionotropic, NMDA 2A polyclonal antibody.

Caprylic Acid Ammonium Sulfate Precipitation purified

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

1.0 mg/ml (lot specific)

Store at -20 degree C

Small volumes of anti-GRIN2A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

NMDA receptor subtype of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. Activation requires binding of agonist to both types of subunits.

Total protein Ab

Immunohistochemistry (IHC)

Immunohistochemistry: 1:20 - 1:200

Immunohistochemical analysis of paraffin-embedded human pancreas using at dilution of 1:100.

144,431 Da[Similar Products]

glutamate ionotropic receptor NMDA type subunit 2A

glutamate receptor ionotropic, NMDA 2A

Glutamate receptor ionotropic, NMDA 2A

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NMDE1_HUMAN

NMDAR2A: a subunit of N-methyl-D-aspartate (NMDA) receptors, members of the glutamate receptor channel superfamily. Possesses high calcium permeability and voltage-dependent sensitivity to magnesium and is modulated by glycine. Plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. Mediates neuronal functions in glutamate neurotransmission.

Protein type: Channel, ligand-gated; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 16p13.2

Cellular Component: cell surface; integral to plasma membrane; N-methyl-D-aspartate selective glutamate receptor complex; plasma membrane

Molecular Function: protein binding; Ras guanyl-nucleotide exchange factor activity; zinc ion binding

Biological Process: glutamate signaling pathway; learning and/or memory; MAPKKK cascade; response to ethanol; synaptic transmission; transport

Disease: Epilepsy, Focal, With Speech Disorder And With Or Without Mental Retardation

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