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Glycogen Synthase, Antibody

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产品名称: Glycogen Synthase, Antibody
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简单介绍

Glycogen Synthase, Antibody


Glycogen Synthase, Antibody  的详细介绍
Product Name

Glycogen Synthase (GYS), Antibody

Full Product Name

Phospho-Glycogen Synthase (Ser645) Antibody

Product Synonym Names
EC 2.4.1.11; glycogen [starch] synthase; muscle; glycogen synthase; muscle
Product Gene Name

anti-GYS antibody

[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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OMIM
138570
3D Structure
ModBase 3D Structure for P13807
Species Reactivity
Human, Mouse, Rat
Specificity
Phospho-Glycogen Synthase (Ser645) Antibody detects endogenous levels of Glycogen Synthase only when phosphorylated at Serine 645
Purity/Purification
Immunogen affinity purified
Form/Format
In phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen
A synthesized peptide derived from human Glycogen Synthase around the phosphorylation site of Serine 645
Preparation and Storage
Store at-20 degree C for 1 year
Other Notes
Small volumes of anti-GYS antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for
anti-GYS antibody
GYS1 muscle glycogen synthase 1. Transfers glucosyl residue from UDP-glucose to glycogen. Regulated allosterically by glucose-6-phosphate, and by PKA-mediated phosphorylation.
Applications Tested/Suitable for anti-GYS antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-GYS antibody
WB: 1:500-1:2000
IHC: 1:50-1:200

Western Blot (WB) of anti-GYS antibody
Western blot analysis of Glycogen Synthase phosphorylation expression in PMA treated NIH-3T3 whole cell lysates, The lane on the left is treated with the antigen-specific peptide.
anti-GYS antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for GYS. It may not necessarily be applicable to this product.
NCBI GI #
239049591
NCBI GeneID
2997
NCBI Accession #
NP_001155059.1 [Other Products]
NCBI GenBank Nucleotide #
NM_001161587.1 [Other Products]
UniProt Primary Accession #
P13807 [Other Products]
UniProt Secondary Accession #
Q9BTT9[Other Products]
UniProt Related Accession #
P13807[Other Products]
Molecular Weight
83; 89kDa
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NCBI Official Full Name
glycogen
NCBI Official Synonym Full Names
glycogen synthase 1
NCBI Official Symbol
GYS1  [Similar Products]
NCBI Official Synonym Symbols
GSY; GYS
  [Similar Products]
NCBI Protein Information
glycogen [starch] synthase, muscle
UniProt Protein Name
Glycogen [starch] synthase, muscle
Protein Family
Glycogen synthase
UniProt Gene Name
GYS1  [Similar Products]
UniProt Synonym Gene Names
GYS  [Similar Products]
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NCBI Summary for GYS
The protein encoded by this gene catalyzes the addition of glucose monomers to the growing glycogen molecule through the formation of alpha-1,4-glycoside linkages. Mutations in this gene are associated with muscle glycogen storage disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
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UniProt Comments for GYS
Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.
Research Articles on GYS
1. Insulin-stimulated glycogen synthase (GS) activity was completely ablated during hyperinsulinemic hypoglycemia, and catecholamine signaling via cAMP-dependent protein kinase (PKA) and phosphorylation of inhibiting sites on GS all increased.
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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