Product Name
Glycogen synthase 1 (GYS1), Monoclonal Antibody
Full Product Name
Phospho-Glycogen synthase 1 (S641)
Product Synonym Names
Glycogen [starch] synthase, muscle
Product Gene Name
anti-GYS1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P13807
Species Reactivity
Human, Mouse
Purity/Purification
ProA affinity purified
Immunogen
Synthetic peptide conjugated to Keyhole Limpet Haemocyanin (KLH)
Storage Buffer
1*TBS (pH7.4), 1% BSA, 40% Glycerol.
Preservative
0.05% Sodium Azide.
Preparation and Storage
Aliquot and store at-20 degree C. Avoid repeated freeze/thaw cycles.
Other Notes
Small volumes of anti-GYS1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-GYS1 antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Immunoprecipitation (IP)
NCBI/Uniprot data below describe general gene information for GYS1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001155059.1
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NCBI GenBank Nucleotide #
NM_001161587.1
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UniProt Primary Accession #
P13807
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UniProt Secondary Accession #
Q9BTT9[Other Products]
UniProt Related Accession #
P13807[Other Products]
Molecular Weight
76,483 Da
NCBI Official Full Name
glycogen
NCBI Official Synonym Full Names
glycogen synthase 1
NCBI Official Symbol
GYS1 [Similar Products]
NCBI Official Synonym Symbols
GSY; GYS
[Similar Products]
NCBI Protein Information
glycogen [starch] synthase, muscle
UniProt Protein Name
Glycogen [starch] synthase, muscle
Protein Family
Glycogen synthase
UniProt Gene Name
GYS1 [Similar Products]
UniProt Synonym Gene Names
GYS [Similar Products]
NCBI Summary for GYS1
The protein encoded by this gene catalyzes the addition of glucose monomers to the growing glycogen molecule through the formation of alpha-1,4-glycoside linkages. Mutations in this gene are associated with muscle glycogen storage disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
UniProt Comments for GYS1
Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.
Research Articles on GYS1
1. Insulin-stimulated glycogen synthase (GS) activity was completely ablated during hyperinsulinemic hypoglycemia, and catecholamine signaling via cAMP-dependent protein kinase (PKA) and phosphorylation of inhibiting sites on GS all increased.
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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