Product Name
Retinal Outer Segment Membrane Protein 1 (ROM1), Recombinant Protein
Full Product Name
Recombinant Retinal Outer Segment Membrane Protein 1 (ROM1)
Product Synonym Names
ROM; ROSP1; TSPAN23; Rod Outer Segment Membrane Protein; Tetraspanin-23
Product Gene Name
ROM1 recombinant protein
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P32958
Purity/Purification
> 90%
Form/Format
Freeze-dried powder
Buffer Formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Source Note
Prokaryotic expression
Endotoxin Level
<1.0EU per 1ug (determined by the LAL method)
Subcellular Location
Membrane; Multi-pass membrane protein
Usage
Reconstitute in PBS or others.
Preparation and Storage
Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
ISO Certification
Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customerâs specifications, please inquire.
Other Notes
Small volumes of ROM1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for ROM1 recombinant protein
Recombinant Protein
Applications Tested/Suitable for ROM1 recombinant protein
Positive Control, Immunogen, SDS-PAGE, Western Blot (WB)
SDS-Page of ROM1 recombinant protein
NCBI/Uniprot data below describe general gene information for ROM1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_033099.3
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NCBI GenBank Nucleotide #
NM_009073.4
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UniProt Primary Accession #
P32958
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UniProt Related Accession #
P32958[Other Products]
NCBI Official Full Name
rod outer segment membrane protein 1
NCBI Official Synonym Full Names
rod outer segment membrane protein 1
NCBI Official Symbol
Rom1 [Similar Products]
NCBI Official Synonym Symbols
Rom-1; Rosp1; M101156; Tspan23; Rgsc1156
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NCBI Protein Information
rod outer segment membrane protein 1
UniProt Protein Name
Rod outer segment membrane protein 1
Protein Family
Rhomboid-like protease
UniProt Gene Name
Rom1 [Similar Products]
UniProt Synonym Gene Names
Rom-1; ROSP1 [Similar Products]
UniProt Comments for ROM1
ROM1: May function as an adhesion molecule involved in stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. It is essential for disk morphogenesis. Defects in ROM1 may cause retinitis pigmentosa (RP); when associated with defects in PRPH2. Belongs to the PRPH2/ROM1 family.
Protein type: Cell surface; Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 19 A|19 6.03 cM
Cellular Component: photoreceptor outer segment
Biological Process: regulation of gene expression; retina morphogenesis in camera-type eye
Research Articles on ROM1
1. ROM1 overexpression leads to negative effects on cone outer segments ultrastructure and function.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.