Product Name
ATG16 autophagy related 16-like 1 (ATG16L1), Polyclonal Antibody
Full Product Name
Rabbit anti-human ATG16 autophagy related 16-like 1 (S. cerevisiae) polyclonal Antibody
Product Synonym Names
ATG16 autophagy related 16-like 1 (S. cerevisiae); ATG16L1; APG16L; ATG16L; FLJ00045; FLJ10035; FLJ10828; FLJ22677; IBD10; WDR30
Product Gene Name
anti-ATG16L1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Storage Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-70133 / sc-70134
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-ATG16L1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-ATG16L1 antibody
ELISA (EIA), Western Blot (WB)
NCBI/Uniprot data below describe general gene information for ATG16L1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_110430.5
[Other Products]
NCBI GenBank Nucleotide #
NM_030803.6
[Other Products]
UniProt Secondary Accession #
Q6IPN1; Q6UXW4; Q6ZVZ5; Q8NCY2; Q96JV5; Q9H619; A3EXK9; A3EXL0; B6ZDH0[Other Products]
UniProt Related Accession #
Q676U5[Other Products]
Molecular Weight
49,486 Da[Similar Products]
NCBI Official Full Name
autophagy-related protein 16-1 isoform 1
NCBI Official Synonym Full Names
autophagy related 16-like 1 (S. cerevisiae)
NCBI Official Symbol
ATG16L1 [Similar Products]
NCBI Official Synonym Symbols
IBD10; WDR30; APG16L; ATG16A; ATG16L
[Similar Products]
NCBI Protein Information
autophagy-related protein 16-1; APG16L beta; WD repeat domain 30; ATG16 autophagy related 16-like 1
UniProt Protein Name
Autophagy-related protein 16-1
UniProt Synonym Protein Names
APG16-like 1
Protein Family
Autophagy-related protein
UniProt Gene Name
ATG16L1 [Similar Products]
UniProt Synonym Gene Names
APG16L [Similar Products]
UniProt Entry Name
A16L1_HUMAN
NCBI Summary for ATG16L1
The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2010]
UniProt Comments for ATG16L1
ATG16: Plays an essential role in autophagy. Homooligomer. Interacts with ATG5. Part of either the minor and major complexes respectively composed of 4 sets of ATG12-ATG5 and ATG16L1 (400 kDa) or 8 sets of ATG12-ATG5 and ATG16L1 (800 kDa). Belongs to the WD repeat ATG16 family. 5 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, peripheral; Adaptor/scaffold; Autophagy
Chromosomal Location of Human Ortholog: 2q37.1
Cellular Component: pre-autophagosomal structure membrane; autophagic vacuole; axoneme
Molecular Function: identical protein binding; protein binding
Biological Process: protein transport; protein homooligomerization; autophagic vacuole formation
Disease: Inflammatory Bowel Disease 10
Research Articles on ATG16L1
1. The ATG16L1 T300A polymorphism defines a specific subtype of patients with Crohn's disease, characterised by Paneth cell endoplasmic reticulum stress even during quiescent disease.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
