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2', 3'-Cyclic Nucleotide 3'-Phosphodiesterase (CNP), Polyclonal Antibody

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产品名称: 2', 3'-Cyclic Nucleotide 3'-Phosphodiesterase (CNP), Polyclonal Antibody
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简单介绍

2', 3'-Cyclic Nucleotide 3'-Phosphodiesterase (CNP), Polyclonal Antibody


2', 3'-Cyclic Nucleotide 3'-Phosphodiesterase (CNP), Polyclonal Antibody  的详细介绍
Product Name

2', 3'-Cyclic Nucleotide 3'-Phosphodiesterase (CNP), Polyclonal Antibody

Full Product Name

HRP-Linked Polyclonal Antibody to 2', 3'-Cyclic Nucleotide 3'-Phosphodiesterase (CNP)

Product Synonym Names
2, 3CNP; 2, 3-CNP; CNPCNP1; Cyclic-CMP Phosphodiesterase; 2', 3'-Cyclic AMP Phosphodiesterase; CNPase; 2':3'-CNMP-3'-ase
Product Gene Name

anti-CNP antibody

[Similar Products]
Matching Pairs
Unconjugated Antibody: 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase (MBS2033860)
HRP Conjugated Antibody: 2', 3'-Cyclic Nucleotide 3'-Phosphodiesterase (CNP) (MBS2064440)
Matching Pairs
HRP Conjugated Antibody: 2', 3'-Cyclic Nucleotide 3'-Phosphodiesterase (CNP) (MBS2064440)
Immunogen: 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase (MBS2034355)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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3D Structure
ModBase 3D Structure for P13233
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Mouse
Concentration
200ug/ml (lot specific)
Immunogen
CNP (Tyr110~Glu365)
Conjugation
HRP
Unconjugated Antibody
The unconjugated antibody version of this item is also available as catalog #MBS2033860
ISO Certification
Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Other Notes
Small volumes of anti-CNP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Applications Tested/Suitable for anti-CNP antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (ELISA)
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NCBI/Uniprot data below describe general gene information for CNP. It may not necessarily be applicable to this product.
NCBI GI #
57977323
NCBI GeneID
25275
NCBI Accession #
NP_036941.1 [Other Products]
NCBI GenBank Nucleotide #
NM_012809.2 [Other Products]
UniProt Primary Accession #
P13233 [Other Products]
UniProt Secondary Accession #
Q4V796; Q64575[Other Products]
UniProt Related Accession #
P13233[Other Products]
Molecular Weight
47,268 Da
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NCBI Official Full Name
2',3'-cyclic-nucleotide 3'-phosphodiesterase
NCBI Official Synonym Full Names
2',3'-cyclic nucleotide 3' phosphodiesterase
NCBI Official Symbol
Cnp  [Similar Products]
NCBI Official Synonym Symbols
CNPF; CNPI; Cnp1; CNPII
  [Similar Products]
NCBI Protein Information
2',3'-cyclic-nucleotide 3'-phosphodiesterase
UniProt Protein Name
2',3'-cyclic-nucleotide 3'-phosphodiesterase
Protein Family
2',3'-cyclic-nucleotide 3'-phosphodiesterase
UniProt Gene Name
Cnp  [Similar Products]
UniProt Synonym Gene Names
Cnp1; CNP; CNPase  [Similar Products]
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NCBI Summary for CNP
microtubule-binding protein that promotes microtubule assembly and may regulate cellular distribution of microtubules [RGD, Feb 2006]
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UniProt Comments for CNP
CNP: May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin. Exists as monomers and homodimers. Belongs to the cyclic nucleotide phosphodiesterase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell development/differentiation; EC 3.1.4.37; Phosphodiesterase

Chromosomal Location of Human Ortholog: 10q31

Cellular Component: cell projection; cytoplasm; extracellular space; membrane; microtubule; microvillus; mitochondrial inner membrane; mitochondrial outer membrane; myelin sheath; nucleoplasm; nucleus; perinuclear region of cytoplasm; plasma membrane; pseudopodium

Molecular Function: 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity; cyclic nucleotide binding

Biological Process: ***** locomotory behavior; aging; axonogenesis; forebrain development; microtubule cytoskeleton organization and biogenesis; oligodendrocyte differentiation; regulation of mitochondrial membrane permeability; response to lipopolysaccharide; response to toxin; substantia nigra development
Research Articles on CNP
1. Perinatal methylmercury exposure reduces the expression of Plp1 and Cnp splice variants in cerebellum of rat pups.
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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