2',3'-Cyclic Nucleotide 3'-Phosphodiesterase, Polyclonal Antibody

2,3CNP; 2,3-CNP; CNPCNP1; Cyclic-CMP Phosphodiesterase; 2',3'-Cyclic AMP Phosphodiesterase; CNPase; 2':3'-CNMP-3'-ase

For Research Use Only. Not for use in diagnostic procedures.

Polyclonal

IgG

Rabbit

The antibody is a rabbit polyclonal antibody raised against CNP. It has been selected for its ability to recognize CNP in immunohistochemical staining and western blotting.

Affinity Chromatography

Supplied as solution form in PBS, pH7.4, Containing 0.02% NaN3, 50% glycerol.

200ug/ml (lot specific)

Store at 4 degree C for frequent use. Stored at -20 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.

Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.

Small volumes of anti-CNP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA)

Western blotting: 1:50-400
Immunohistochemistry in formalin fixed frozen section: 1:50-500
Enzyme-linked Immunosorbent Assay: 1:100-1:5000

Western Blot: Sample: Mouse Cerebellum lysate; Primary Ab: 1ug/ml Rabbit Anti-Mouse CNP Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody

Western Blot: Sample: Recombinant protein.

DAB staining on fromalin fixed paraffin- embedded brain tissue)

DAB staining on IHC-P; Samples: Mouse Cerebrum Tissue)

44,654 Da

2',3'-cyclic nucleotide 3' phosphodiesterase

2',3'-cyclic-nucleotide 3'-phosphodiesterase

2',3'-cyclic-nucleotide 3'-phosphodiesterase

Cnp1; CNP; CNPase  [Similar Products]

CNP: May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin. Exists as monomers and homodimers. Belongs to the cyclic nucleotide phosphodiesterase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell development/differentiation; EC 3.1.4.37; Phosphodiesterase

Chromosomal Location of Human Ortholog: 11 D|11 63.47 cM

Cellular Component: cell projection; cytoplasm; extracellular exosome; extracellular space; membrane; microtubule; microvillus; mitochondrial inner membrane; mitochondrial outer membrane; myelin sheath; perinuclear region of cytoplasm; plasma membrane; pseudopodium

Molecular Function: 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity; cyclic nucleotide binding; hydrolase activity; RNA binding

Biological Process: ***** locomotory behavior; axonogenesis; cyclic nucleotide catabolic process; microtubule cytoskeleton organization; oligodendrocyte differentiation; regulation of mitochondrial membrane permeability; response to toxin

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.