Full Product Name
MOUSE ANTI HUMAN CD71
Product Gene Name
anti-CD71 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P02786
Form/Format
Purified
Purified IgG - liquid
Concentration
IgG concentration 1.0 mg/ml (lot specific)
Perservative Stabilisers
0.09% Sodium Azide
Preparation
Immunogen
KGI cell line
Fusion Partners
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Other Notes
Small volumes of anti-CD71 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CD71 antibody
Mouse anti Human CD71 antibody, clone DF1513 recognizes the human CD71 cell surface antigen, a 190kDa homodimeric glycoprotein expressed by proliferating cells. CD71 is also known as the transferrin receptor.
Applications Tested/Suitable for anti-CD71 antibody
Flow cytometry (FC/FACS), Immunofluorescence (IF)
Application Notes for anti-CD71 antibody
Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul.
Flow Cytometry: Minimum Dilution: 1/10; Maximum Dilution: 1/25
Testing Data #1 of anti-CD71 antibody
Staining of MOLT4 (human acute lymphoblastic leukemia) cells with Mouse anti Human CD71: FITC (MBS224478)
Testing Data #2 of anti-CD71 antibody
Staining of Jurkat cells with Mouse anti Human CD71:RPE (MBS224474)
Testing Data #3 of anti-CD71 antibody
Staining of KG1 cells with Mouse anti Human CD71:Alexa Fluor
R 647 (MBS224473)
NCBI/Uniprot data below describe general gene information for CD71. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001121620.1
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NCBI GenBank Nucleotide #
NM_001128148.1
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UniProt Primary Accession #
P02786
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UniProt Secondary Accession #
Q1HE24; Q59G55; Q9UCN0; Q9UCU5; Q9UDF9; Q9UK21; D3DXB0[Other Products]
UniProt Related Accession #
P02786[Other Products]
Molecular Weight
84,871 Da
NCBI Official Full Name
transferrin receptor protein 1
NCBI Official Synonym Full Names
transferrin receptor
NCBI Official Symbol
TFRC [Similar Products]
NCBI Official Synonym Symbols
T9; TR; TFR; p90; CD71; TFR1; TRFR
[Similar Products]
NCBI Protein Information
transferrin receptor protein 1; transferrin receptor (p90, CD71)
UniProt Protein Name
Transferrin receptor protein 1
UniProt Synonym Protein Names
T9; p90; CD_antigen: CD71Transferrin receptor protein 1, serum form; sTfR
UniProt Gene Name
TFRC [Similar Products]
UniProt Synonym Gene Names
TR; TfR; TfR1; Trfr; sTfR [Similar Products]
UniProt Entry Name
TFR1_HUMAN
UniProt Comments for CD71
TfR: the transferrin receptor. Regulates the cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied receptors into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system.
Protein type: Cell surface; Receptor, misc.; Membrane protein, integral
Chromosomal Location of Human Ortholog: 3q29
Cellular Component: extracellular space; cell surface; intracellular membrane-bound organelle; integral to plasma membrane; cytoplasmic membrane-bound vesicle; extracellular region; coated pit; recycling endosome; membrane; perinuclear region of cytoplasm; melanosome; plasma membrane; vesicle; endosome; external side of plasma membrane
Molecular Function: identical protein binding; protein binding; transferrin receptor activity; double-stranded RNA binding
Biological Process: receptor-mediated endocytosis; viral reproduction; cellular iron ion homeostasis; transferrin transport; positive regulation of bone resorption; osteoclast differentiation; regulation of cell growth; transmembrane transport; regulation of cell proliferation
Research Articles on CD71
1. CD71 is useful for the evaluation of differentiation stage for AML cells.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
