Product Name
CTAG1A, Blocking Peptide
Full Product Name
CTAG1A Antibody (N-term) Blocking peptide
Product Synonym Names
Cancer/testis antigen 1; Autoimmunogenic cancer/testis antigen NY-ESO-1; Cancer/testis antigen 61; CT61; L antigen family member 2; LAGE-2; CTAG1A; CTAG; CTAG1; ESO1; LAGE2; LAGE2A
Product Gene Name
CTAG1A blocking peptide
[Similar Products]
Product Synonym Gene Name
CTAG; CTAG1; ESO1; LAGE2; LAGE2A[Similar Products]
Antibody/Peptide Pairs
CTAG1A peptide (MBS9219973) is used for blocking the activity of CTAG1A antibody (MBS9211893)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P78358
Specificity
The synthetic peptide sequence used to generate the antibody was selected from the N-term region of CTAG1A. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Cellular Location
Cytoplasm.
Tissue Location
Expressed in testis and ovary and in a wide variety of cancers. Detected in uterine myometrium. Expressed from 18 weeks until birth in human fetal testis. In the ***** testis, is strongly expressed in spermatogonia and in primary spermatocytes, but not in post-meiotic cells or in testicular somatic cells (at protein level).
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Other Notes
Small volumes of CTAG1A blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for CTAG1A. It may not necessarily be applicable to this product.
NCBI Accession #
P78358.1
[Other Products]
UniProt Primary Accession #
P78358
[Other Products]
UniProt Secondary Accession #
Q7LBY4; Q9NY13; A1L417; B7WNL9[Other Products]
UniProt Related Accession #
P78358[Other Products]
Molecular Weight
16,192 Da
NCBI Official Full Name
Cancer/testis antigen 1
NCBI Official Synonym Full Names
cancer/testis antigen 1B
NCBI Official Symbol
CTAG1B [Similar Products]
NCBI Official Synonym Symbols
CTAG; ESO1; CT6.1; CTAG1; LAGE-2; LAGE2B; NY-ESO-1
[Similar Products]
NCBI Protein Information
cancer/testis antigen 1
UniProt Protein Name
Cancer/testis antigen 1
UniProt Synonym Protein Names
Autoimmunogenic cancer/testis antigen NY-ESO-1; Cancer/testis antigen 6.1; CT6.1; L antigen family member 2; LAGE-2
Protein Family
Cancer/testis antigen
UniProt Gene Name
CTAG1A [Similar Products]
UniProt Synonym Gene Names
CTAG; CTAG1; ESO1; LAGE2; LAGE2A; CT6.1; LAGE-2 [Similar Products]
UniProt Entry Name
CTG1B_HUMAN
NCBI Summary for CTAG1A
The protein encoded by this gene is an antigen that is overexpressed in many cancers but that is also expressed in normal testis. This gene is found in a duplicated region of the X-chromosome and therefore has a neighboring gene of identical sequence. [provided by RefSeq, Jan 2012]
UniProt Comments for CTAG1A
CTAG1B: is an antigen that is overexpressed in many cancers but that is also expressed in normal testis. This gene is found in a duplicated region of the X-chromosome and therefore has a neighboring gene of identical sequence. [provided by RefSeq, Jan 2012]
Protein type: Cancer Testis Antigen (CTA)
Chromosomal Location of Human Ortholog: Xq28
Cellular Component: cytoplasm
Molecular Function: protein binding
Research Articles on CTAG1A
1. CTAs (MAGE-A4, NY-ESO-1, MAGE-A10) were more likely expressed in patients with squamous cell carcinoma of the lung and when CTAs combined with CD133, they can be better prognostic factors.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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