Product Name
COL7A1, Polyclonal Antibody
Full Product Name
COL7A1 Polyclonal Antibody
Product Gene Name
anti-COL7A1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q02388
Other Notes
Small volumes of anti-COL7A1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for COL7A1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000085.1
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NCBI GenBank Nucleotide #
NM_000094.3
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UniProt Primary Accession #
Q02388
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UniProt Secondary Accession #
Q14054; Q16507[Other Products]
UniProt Related Accession #
Q02388[Other Products]
Molecular Weight
292,267 Da
NCBI Official Full Name
collagen alpha-1(VII) chain
NCBI Official Synonym Full Names
collagen type VII alpha 1 chain
NCBI Official Symbol
COL7A1 [Similar Products]
NCBI Official Synonym Symbols
EBD1; EBR1; EBDCT; NDNC8
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NCBI Protein Information
collagen alpha-1(VII) chain
UniProt Protein Name
Collagen alpha-1(VII) chain
UniProt Synonym Protein Names
Long-chain collagen; LC collagen
UniProt Gene Name
COL7A1 [Similar Products]
UniProt Synonym Gene Names
LC collagen [Similar Products]
NCBI Summary for COL7A1
This gene encodes the alpha chain of type VII collagen. The type VII collagen fibril, composed of three identical alpha collagen chains, is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Mutations in this gene are associated with all forms of dystrophic epidermolysis bullosa. In the absence of mutations, however, an acquired form of this disease can result from an autoimmune response made to type VII collagen. [provided by RefSeq, Jul 2008]
UniProt Comments for COL7A1
Stratified squamous epithelial basement membrane protein that forms anchoring fibrils which may contribute to epithelial basement membrane organization and adherence by interacting with extracellular matrix (ECM) proteins such as type IV collagen.
Research Articles on COL7A1
1. expression restored to recessive dystrophic epidermolysis bullosa skin by topical gene therapy
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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