LIM/homeobox protein Lhx4 (LHX4), ELISA Kit

For Research Use Only. Not for use in diagnostic procedures.

Store all reagents at 2-8 degree C.

We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.

Small volumes of LHX4 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS7202162 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the LIM/homeobox protein Lhx4 (LHX4) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing LHX4. The ELISA analytical biochemical technique of the MBS7202162 kit is based on LHX4 antibody-LHX4 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect LHX4 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, LHX4. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Epigenetics and Nuclear Signaling

43,124 Da[Similar Products]

LIM homeobox 4

LIM/homeobox protein Lhx4; LIM homeobox protein 4

LIM/homeobox protein Lhx4

LIM homeobox protein 4  [Similar Products]

LHX4_HUMAN

This gene encodes a member of a large protein family which contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein is a transcription factor involved in the control of differentiation and development of the pituitary gland. Mutations in this gene cause combined pituitary hormone deficiency 4. [provided by RefSeq, Dec 2010]

LHX4: May play a critical role in the development of respiratory control mechanisms and in the normal growth and maturation of the lung. Defects in LHX4 are the cause of pituitary hormone deficiency combined type 4 (CPHD4); also known as short stature pituitary and cerebellar defects and small sella turcica. The disorder is characterized by short stature, pituitary and cerebellar defects, and small transverse depression crossing the midline on the superior surface of the body of the sphenoid bone which houses the pituitary gland. A chromosomal aberration involving LHX4 may be a cause of acute lymphoblastic leukemia. Translocation t(1;14)(q25;q32) with IGHG1.

Protein type: Oncoprotein; DNA-binding

Chromosomal Location of Human Ortholog: 1q25.2

Cellular Component: nucleus

Molecular Function: zinc ion binding; sequence-specific DNA binding

Biological Process: organ morphogenesis; transcription, DNA-dependent; regulation of transcription, DNA-dependent; medial motor column neuron differentiation; motor axon guidance; placenta development; negative regulation of apoptosis

Disease: Pituitary Hormone Deficiency, Combined, 4

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