Full Product Name
FAAH2 Antibody
Product Synonym Names
AMDD
Product Gene Name
anti-FAAH2 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q6GMR7
Specificity
The antibody detects endogenous levels of total FAAH2 protein.
Purity/Purification
Antigen affinity purification.
Form/Format
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Concentration
1.5 mg/ml (lot specific)
Immunogen Type
Recombinant Protein
Immunogen Description
Fusion protein corresponding to residues near the C terminal of human fatty acid amide hydrolase 2
Preparation and Storage
Store at -20 degree C
Other Notes
Small volumes of anti-FAAH2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-FAAH2 antibody
This gene encodes a fatty acid amide hydrolase that shares a conserved protein motif with the amidase signature family of enzymes. The encoded enzyme is able to catalyze the hydrolysis of a broad range of bioactive lipids, including those from the three main classes of fatty acid amides; N-acylethanolamines, fatty acid primary amides and N-acyl amino acids. This enzyme has a preference for monounsaturated acyl chains as a substrate.
Product Categories/Family for anti-FAAH2 antibody
Total protein Ab
Applications Tested/Suitable for anti-FAAH2 antibody
Immunohistochemistry (IHC)
Application Notes for anti-FAAH2 antibody
Immunohistochemistry: 1:50-1:200
Immunohistochemistry (IHC) of anti-FAAH2 antibody
Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using at dilution 1/30.
Immunohistochemistry (IHC) of anti-FAAH2 antibody
Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue using at dilution 1/30.
NCBI/Uniprot data below describe general gene information for FAAH2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_777572.2
[Other Products]
NCBI GenBank Nucleotide #
NM_174912.3
[Other Products]
UniProt Primary Accession #
Q6GMR7
[Other Products]
UniProt Secondary Accession #
Q86VT2; Q96N98[Other Products]
UniProt Related Accession #
Q6GMR7[Other Products]
Molecular Weight
58,304 Da
NCBI Official Full Name
fatty-acid amide hydrolase 2
NCBI Official Synonym Full Names
fatty acid amide hydrolase 2
NCBI Official Symbol
FAAH2 [Similar Products]
NCBI Official Synonym Symbols
AMDD
[Similar Products]
NCBI Protein Information
fatty-acid amide hydrolase 2
UniProt Protein Name
Fatty-acid amide hydrolase 2
UniProt Synonym Protein Names
Amidase domain-containing protein; Anandamide amidohydrolase 2; Oleamide hydrolase 2
Protein Family
Fatty-acid amide hydrolase
UniProt Gene Name
FAAH2 [Similar Products]
UniProt Synonym Gene Names
AMDD [Similar Products]
UniProt Entry Name
FAAH2_HUMAN
NCBI Summary for FAAH2
This gene encodes a fatty acid amide hydrolase that shares a conserved protein motif with the amidase signature family of enzymes. The encoded enzyme is able to catalyze the hydrolysis of a broad range of bioactive lipids, including those from the three main classes of fatty acid amides; N-acylethanolamines, fatty acid primary amides and N-acyl amino acids. This enzyme has a preference for monounsaturated acyl chains as a substrate.[provided by RefSeq, Sep 2009]
UniProt Comments for FAAH2
FAAH2: Degrades bioactive fatty acid amides like oleamide, the endogenous cannabinoid, anandamide and myristic amide to their corresponding acids, thereby serving to terminate the signaling functions of these molecules. Hydrolyzes monounsaturated substrate anandamide preferentially as compared to polyunsaturated substrates. Belongs to the amidase family.
Protein type: Membrane protein, integral; Hydrolase; EC 3.5.1.99
Chromosomal Location of Human Ortholog: Xp11.21
Cellular Component: integral to membrane
Molecular Function: carbon-nitrogen ligase activity, with glutamine as amido-N-donor; hydrolase activity
Biological Process: metabolic process
Research Articles on FAAH2
1. results establish FAAH-2 as a bone fide N-acylethanolamine-catabolizing enzyme and suggest that inactivation is spatially separated in cells of higher mammals
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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