Collagen alpha-1(VII) chain, ELISA Kit

Collagen alpha-1(VII) chain; Long-chain collagen; LC collagen; Col7a1

For Research Use Only. Not for use in diagnostic procedures.

For long term storage, please store the entire kit at -20 degree C.

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Small volumes of Col7a1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS2885354 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Collagen alpha-1(VII) chain (Col7a1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing Col7a1. The ELISA analytical biochemical technique of the MBS2885354 kit is based on Col7a1 antibody-Col7a1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Col7a1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, Col7a1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

295,232 Da

collagen, type VII, alpha 1

collagen alpha-1(VII) chain

Collagen alpha-1(VII) chain

LC collagen  [Similar Products]

CO7A1_MOUSE

COL7A1: the alpha chain of type VII collagen, an extra-cellular basement membrane protein restricted to the zone beneath stratified squamous epithelia. Type VII collagen fibrils are composed of three identical alpha collagen chains. Forms anchoring fibrils, which may contribute to epithelial basement membrane organization and adherence by interacting with extracellular matrix (ECM) proteins such as type IV collagen. Dystrophic epidermolysis bullosa can result from defects in this protein or an autoimmune response made to type VII collagen. Homotrimer. Interacts with MIA3, facilitating its loading into transport carriers and subsequent secretion. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Extracellular matrix; Secreted; Inhibitor; Secreted, signal peptide

Cellular Component: basement membrane; collagen; extracellular region; extracellular space; proteinaceous extracellular matrix

Molecular Function: identical protein binding; protease inhibitor activity; serine-type endopeptidase inhibitor activity

Biological Process: cell adhesion; negative regulation of peptidase activity

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