GRK1, ELISA Kit

RHOK; RK; Rhodopsin kinase; kinase GRK1

For Research Use Only. Not for use in diagnostic procedures.

Two 96-Well Plates

Store at 4 degree C.

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.

Small volumes of GRK1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9501303 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the GRK1, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing GRK1. The ELISA analytical biochemical technique of the MBS9501303 kit is based on GRK1 antibody-GRK1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect GRK1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, GRK1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Cell Based ELISA Kit

63526

G protein-coupled receptor kinase 1

rhodopsin kinase

Rhodopsin kinase

RK  [Similar Products]

This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates rhodopsin and initiates its deactivation. Defects in GRK1 are known to cause Oguchi disease 2 (also known as stationary night blindness Oguchi type-2). [provided by RefSeq, Jul 2008]

GRK1: a Ser/Thr of the GRK family. Phosphorylates and inactivates photon-activated rhodopsin. LOF mutations lead to type 2 Oguchi disease, a form of night blindness. A link between RHOK and retinitis pigmentosa is now thought to be unlikely

Protein type: AGC group; EC 2.7.11.14; GRK family; GRK subfamily; Kinase, protein; Protein kinase, AGC; Protein kinase, Ser/Thr (non-receptor)

Chromosomal Location of Human Ortholog: 13q34

Molecular Function: ATP binding; G-protein coupled receptor kinase activity; protein kinase activity; rhodopsin kinase activity

Biological Process: protein autophosphorylation; regulation of G-protein coupled receptor protein signaling pathway; regulation of rhodopsin mediated signaling; rhodopsin mediated signaling pathway; visual perception

Disease: Oguchi Disease 2

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