Product Name
RNASEH2C, Polyclonal Antibody
Full Product Name
RNASEH2C Antibody, HRP conjugated
Product Synonym Names
Ribonuclease H2 subunit C; RNase H2 subunit C; Aicardi-Goutieres syndrome 3 protein; AGS3; RNase H1 small subunit; Ribonuclease HI subunit C; RNASEH2C; AYP1
Product Gene Name
anti-RNASEH2C antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q8TDP1
Purity/Purification
>95%, Protein G purified
Immunogen
Recombinant Human Ribonuclease H2 subunit C protein (1-164AA)
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-RNASEH2C antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-RNASEH2C antibody
Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
Product Categories/Family for anti-RNASEH2C antibody
Epigenetics and Nuclear Signaling
Applications Tested/Suitable for anti-RNASEH2C antibody
ELISA (EIA)
NCBI/Uniprot data below describe general gene information for RNASEH2C. It may not necessarily be applicable to this product.
NCBI Accession #
NP_115569.2
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NCBI GenBank Nucleotide #
NM_032193.3
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UniProt Primary Accession #
Q8TDP1
[Other Products]
UniProt Secondary Accession #
Q9H7F5[Other Products]
UniProt Related Accession #
Q8TDP1[Other Products]
Molecular Weight
17,840 Da
NCBI Official Full Name
ribonuclease H2 subunit C
NCBI Official Synonym Full Names
ribonuclease H2 subunit C
NCBI Official Symbol
RNASEH2C [Similar Products]
NCBI Official Synonym Symbols
AGS3; AYP1
[Similar Products]
NCBI Protein Information
ribonuclease H2 subunit C
UniProt Protein Name
Ribonuclease H2 subunit C
UniProt Synonym Protein Names
Aicardi-Goutieres syndrome 3 protein; AGS3; RNase H1 small subunit; Ribonuclease HI subunit C
Protein Family
Ribonuclease
UniProt Gene Name
RNASEH2C [Similar Products]
UniProt Synonym Gene Names
AYP1; RNase H2 subunit C; AGS3 [Similar Products]
NCBI Summary for RNASEH2C
This gene encodes a ribonuclease H subunit that can cleave ribonucleotides from RNA:DNA duplexes. Mutations in this gene cause Aicardi-Goutieres syndrome-3, a disease that causes severe neurologic dysfunction. A pseudogene for this gene has been identified on chromosome Y, near the sex determining region Y (SRY) gene. [provided by RefSeq, Jul 2008]
UniProt Comments for RNASEH2C
Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
Research Articles on RNASEH2C
1. This study reviewed that Neurologic Phenotypes Associated with Mutations in RNASEH2C in patients with Aicardi-Goutieres Syndrome.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
