Full Product Name
PHYH Polyclonal Antibody
Product Synonym Names
LN1; LNAP1; PAHX; PHYH1; RD
Product Gene Name
anti-PHYH antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
MEQLRAAARL QIVLGHLGRP SAGAVVAHPT SGTISSASFH PQQFQYTLDN NVLTLEQRKF YEENGFLVIK NLVPDADIQR FRNEFEKICR KEVKPLGLTV MRDVTISKSE YAPSEKMITK VQDFQEDKEL FRYCTLPEIL KYVECFTGPN IMAMHTMLIN KPPDSGKKTS RHPLHQDLHY FPFRPSDLIV CAWTAMEHIS RNNGCLVVLP GTHKGSLKPH DYPKWEGGVN KMFHGIQDYE ENKARVHLVM EKGDT
3D Structure
ModBase 3D Structure for O14832
Species Reactivity
Mouse, Rat
Purity/Purification
Affinity Purification
Immunogen
Recombinant protein of human PHYH
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Cellular Location
Peroxisome
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
Other Notes
Small volumes of anti-PHYH antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-PHYH antibody
This gene is a member of the PhyH family and encodes a peroxisomal protein that is involved in the alpha-oxidation of 3-methyl branched fatty acids. Specifically, this protein converts phytanoyl-CoA to 2-hydroxyphytanoyl-CoA. Mutations in this gene have been associated with Refsum disease (RD) and deficient protein activity has been associated with Zellweger syndrome and rhizomelic chondrodysplasia punctata. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Product Categories/Family for anti-PHYH antibody
Polyclonal Antibodies
Applications Tested/Suitable for anti-PHYH antibody
Western Blot (WB)
Application Notes for anti-PHYH antibody
WB: 1:500 - 1:2000
NCBI/Uniprot data below describe general gene information for PHYH. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001032626.1
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NCBI GenBank Nucleotide #
NM_001037537.1
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UniProt Primary Accession #
O14832
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UniProt Secondary Accession #
A8MTS8; B1ALH5[Other Products]
UniProt Related Accession #
O14832[Other Products]
Molecular Weight
27kDa/38kDa
NCBI Official Full Name
phytanoyl-CoA dioxygenase, peroxisomal isoform b
NCBI Official Synonym Full Names
phytanoyl-CoA 2-hydroxylase
NCBI Official Symbol
PHYH [Similar Products]
NCBI Official Synonym Symbols
RD; LN1; PAHX; LNAP1; PHYH1
[Similar Products]
NCBI Protein Information
phytanoyl-CoA dioxygenase, peroxisomal
UniProt Protein Name
Phytanoyl-CoA dioxygenase, peroxisomal
UniProt Synonym Protein Names
Phytanic acid oxidase; Phytanoyl-CoA alpha-hydroxylase; PhyH
Protein Family
Phytanoyl-CoA dioxygenase
UniProt Gene Name
PHYH [Similar Products]
UniProt Synonym Gene Names
PAHX; PhyH [Similar Products]
NCBI Summary for PHYH
This gene is a member of the PhyH family and encodes a peroxisomal protein that is involved in the alpha-oxidation of 3-methyl branched fatty acids. Specifically, this protein converts phytanoyl-CoA to 2-hydroxyphytanoyl-CoA. Mutations in this gene have been associated with Refsum disease (RD) and deficient protein activity has been associated with Zellweger syndrome and rhizomelic chondrodysplasia punctata. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
UniProt Comments for PHYH
Converts phytanoyl-CoA to 2-hydroxyphytanoyl-CoA.
Research Articles on PHYH
1. T (p.Pro29Ser), c.135-2A>G, and c.768del63bp (p.Phe257Glnfs*16) were found in a family with Refsum's disease.">3 heterozygous variants: c.85C>T (p.Pro29Ser), c.135-2A>G, and c.768del63bp (p.Phe257Glnfs*16) were found in a family with Refsum's disease.
Precautions
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Disclaimer
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