Product Name
Psen2, Blocking Peptide
Full Product Name
Psen2 Peptide - C-terminal region
Product Gene Name
Psen2 blocking peptide
[Similar Products]
Psen2 peptide (MBS3232266) is used for blocking the activity of Psen2 antibody (MBS3207301)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
TAQERNEPIF PALIYSSAMV WTVGMAKLDP SSQGALQLPY DPEMEEDSYD
3D Structure
ModBase 3D Structure for O88777
Species Reactivity
Rat, Human
Form/Format
Lyophilized powder
Preparation and Storage
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.
Other Notes
Small volumes of Psen2 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
Psen2 blocking peptide
This is a synthetic peptide designed for use in combination with anti-Psen2 Antibody, made
Target Description: This gene mutations in human homolog responsible for chromosome 1-linked familial Alzheimer's disease; expression increased during brain development but decreased in the *****.
Product Categories/Family for Psen2 blocking peptide
Peptide
Applications Tested/Suitable for Psen2 blocking peptide
Western Blot (WB)
NCBI/Uniprot data below describe general gene information for Psen2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_112349
[Other Products]
NCBI GenBank Nucleotide #
NM_031087
[Other Products]
UniProt Primary Accession #
O88777
[Other Products]
UniProt Related Accession #
O88777[Other Products]
NCBI Official Full Name
presenilin-2
NCBI Official Synonym Full Names
presenilin 2
NCBI Official Symbol
Psen2 [Similar Products]
NCBI Protein Information
presenilin-2
UniProt Protein Name
Presenilin-2
Protein Family
Presenilin
UniProt Gene Name
Psen2 [Similar Products]
UniProt Synonym Gene Names
Ps2; Psnl2 [Similar Products]
UniProt Entry Name
PSN2_RAT
NCBI Summary for Psen2
mutations in human homolog responsible for chromosome 1-linked familial Alzheimer's disease; expression increased during brain development but decreased in the ***** [RGD, Feb 2006]
Research Articles on Psen2
1. Downregulating the expression of miR-375, miR-30a, and miR-34a restored PSEN1, PSEN2, and NICD1 production and prevented glucotoxicity-induced impairment of the beta cells.Our findings demonstrated that miRNA-mediated suppression of NICD1 links the presenilin/Notch1 pathway to glucotoxicity in mature pancreatic beta cells
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
