Product Name
Bestrophin-2 (Best2), Recombinant Protein
Full Product Name
Recombinant Mouse Bestrophin-2 (Best2)
Product Gene Name
Best2 recombinant protein
[Similar Products]
Product Synonym Gene Name
Vmd2l1[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-508aa; full length protein
Sequence
MTVTYTARVA NARFGGFSQL LLLWRGSIYK LLWRELLCFL GLYMALSAAY RFLLAEEQKR YFEKLVIYCD QYASLIPVSF VLGFYVTLVV HRWWNQYLCM PLPDALMCIV AGTVHGRDDR GRLYRRTLMR YAGLSAVLIL RSVSTAVFKR FPTIDHVVEA GFMTREERKK FENLNSSYNK YWVPCVWFSS LAAQARREGR IRDNSALKLL LEELNVFRSK CGMLFHYDWI SIPLVYTQVV TIAVYSYFLA CLIGRQFLDP AQGYKDHTLD LCVPIFTLLQ FFFYAGWLKV AEQLINPFGE DDDDFETNFL IDRNFQVSML AVDEMYDDLA MLEKDLYWDA AEARAPYTAA TAFLLQQPSF QGSTFDIALA KEDMQFQRLD GVDGPLGEVH GDFLQRLLPA GAGSVGPLGR RLSLLRRKNS CVSEASTAAS CGCAGAADGG GVECGCGDPL LDPSLREPEL EPPACPEPPA PIPGPTPEPF TTVSIPGPRA PAPPWLPSPI GEEEESPA
3D Structure
ModBase 3D Structure for Q8BGM5
Host
Cell Free Expression
Form/Format
Liquid containing glycerol
Storage Buffer
Tris-based buffer, 50% glycerol.
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Best2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for Best2 recombinant protein
Transmembrane Protein
Application Notes for Best2 recombinant protein
This is a recombinant transmembrane protein expressed in a cell-free expression system.
NCBI/Uniprot data below describe general gene information for Best2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001123666.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001130194.1
[Other Products]
UniProt Primary Accession #
Q8BGM5
[Other Products]
UniProt Secondary Accession #
Q6H1U9; Q8VCM0[Other Products]
UniProt Related Accession #
Q8BGM5[Other Products]
Molecular Weight
57,023 Da
NCBI Official Full Name
bestrophin-2
NCBI Official Synonym Full Names
bestrophin 2
NCBI Official Symbol
Best2 [Similar Products]
NCBI Official Synonym Symbols
Vmd2l1
[Similar Products]
NCBI Protein Information
bestrophin-2
UniProt Protein Name
Bestrophin-2
UniProt Synonym Protein Names
Vitelliform macular dystrophy 2-like protein 1
Protein Family
Bestrophin
UniProt Gene Name
Best2 [Similar Products]
UniProt Synonym Gene Names
Vmd2l1 [Similar Products]
UniProt Entry Name
BEST2_MOUSE
UniProt Comments for Best2
BEST2: Forms calcium-sensitive chloride channels. Permeable to bicarbonate. Belongs to the bestrophin family.
Protein type: Membrane protein, integral; Transporter; Transporter, ion channel; Membrane protein, multi-pass
Cellular Component: cilium; integral to membrane; integral to plasma membrane; membrane; plasma membrane
Molecular Function: chloride channel activity
Biological Process: chloride transport; ion transport; membrane depolarization; transport
Research Articles on Best2
1. Bestrophin-2 mediates bicarbonate transport by goblet cells in mouse colon
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
