Product Name
DNA-directed RNA polymerases I and III subunit RPAC1 (POLR1C), Recombinant Protein
Full Product Name
Recombinant Bovine DNA-directed RNA polymerases I and III subunit RPAC1 (POLR1C)
Product Gene Name
POLR1C recombinant protein
[Similar Products]
Product Synonym Gene Name
POLR1C[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
2-346aa, Full Length of Mature Protein
Sequence
AAAQAVEEMR TRVVLGEFGV RNVHTTDFPG NYSGYDDAWD QDRFEKNFRV DVVHMDENSL EFDMVGIDAA IANAFRRILL AEVPTMAVEK VLVYNNTSIV QDEILAHRLG LIPIHADPRL FEYRNQGDEG GTEIDTLQFR LQVRCTRNPH AAKDSSDPNE LYVNHRVYTR HMTWVPLGNQ ADLFPEGAIR PVHDDILIAQ LRPGQEIDLL MHCVKGIGKD HAKFSPVATA SYRLLPDITL LEPVEGEAAE ELSRCFSPGV IEVQEIQGKK VARVANPRLD TFSREVFRNE KLKKVVRLAR VRDHFIFSVE STGVLPPDVL VSEAIKVLMG KCQRFLDELD AVQMD
3D Structure
ModBase 3D Structure for Q32L22
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of POLR1C recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for POLR1C. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001033213.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001038124.2
[Other Products]
UniProt Primary Accession #
Q32L22
[Other Products]
UniProt Related Accession #
Q32L22[Other Products]
Molecular Weight
39,116 Da
NCBI Official Full Name
DNA-directed RNA polymerases I and III subunit RPAC1
NCBI Official Synonym Full Names
RNA polymerase I subunit C
NCBI Official Symbol
POLR1C [Similar Products]
NCBI Protein Information
DNA-directed RNA polymerases I and III subunit RPAC1
UniProt Protein Name
DNA-directed RNA polymerases I and III subunit RPAC1
Protein Family
DNA-directed RNA polymerases
UniProt Gene Name
POLR1C [Similar Products]
UniProt Synonym Gene Names
DNA-directed RNA polymerase I subunit C; RNA polymerases I and III subunit AC1 [Similar Products]
UniProt Comments for POLR1C
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively. RPAC1 is part of the Pol core element with the central large cleft and probably a clamp element that moves to open and close the cleft ().
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
