Product Name
Dual oxidase (Duox), Recombinant Protein
Full Product Name
Recombinant Drosophila melanogaster Dual oxidase (Duox), partial
Product Gene Name
Duox recombinant protein
[Similar Products]
Product Synonym Gene Name
Duox[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q9VQH2
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Drosophila melanogaster (Fruit fly)
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Duox recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for Duox. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001259968.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001273039.1
[Other Products]
UniProt Primary Accession #
Q9VQH2
[Other Products]
UniProt Secondary Accession #
Q6AWK1[Other Products]
UniProt Related Accession #
Q9VQH2[Other Products]
Molecular Weight
177,690 Da
NCBI Official Full Name
dual oxidase, isoform C
NCBI Official Synonym Full Names
Dual oxidase
NCBI Official Symbol
Duox [Similar Products]
NCBI Official Synonym Symbols
CG3131; Cy; dduox; dDuox; DmelCG3131; duox; DUOX; l(2)23Bb
[Similar Products]
NCBI Protein Information
CG3131 gene product from transcript CG3131-RC
UniProt Protein Name
Dual oxidase
Protein Family
Dual oxidase
UniProt Gene Name
Duox [Similar Products]
UniProt Comments for Duox
Plays a role in innate immunity limiting microbial proliferation in the gut (PubMed:16272120, PubMed:25639794). Acts downstream of a hh-signaling pathway to induce the production of reactive oxygen species (ROS) in response to intestinal bacterial infection (PubMed:25639794). May generate antimicrobial oxidative burst through its peroxidase-like domain (PubMed:16272120).
Research Articles on Duox
1. our results propose that the uracil/Duox pathway promotes bacteria expulsion from the gut through the HOCl-sensitive receptor, TRPA1(A)10b, thereby minimizing the chances that bacteria adapt to survive host defense systems.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
