Product Name
Glycine N-Methyltransferase (GNMT), Antibody
Full Product Name
Mouse Anti Human Glycine N-Methyltransferase
Product Gene Name
anti-GNMT antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Other Notes
Small volumes of anti-GNMT antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-GNMT antibody
MONOCLONAL ANTIBODIES; ANTI-HUMAN ENZYMES
NCBI/Uniprot data below describe general gene information for GNMT. It may not necessarily be applicable to this product.
NCBI Accession #
AAF78289.1
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UniProt Secondary Accession #
Q5T8W2; Q9NNZ1; Q9NS24[Other Products]
UniProt Related Accession #
Q14749[Other Products]
Molecular Weight
32,742 Da
NCBI Official Full Name
glycine N-methyltransferase
NCBI Official Synonym Full Names
glycine N-methyltransferase
NCBI Official Symbol
GNMT [Similar Products]
NCBI Official Synonym Symbols
HEL-S-182mP
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NCBI Protein Information
glycine N-methyltransferase
UniProt Protein Name
Glycine N-methyltransferase
Protein Family
Glycine N-methyltransferase
UniProt Gene Name
GNMT [Similar Products]
UniProt Entry Name
GNMT_HUMAN
UniProt Comments for GNMT
GNMT: Catalyzes the methylation of glycine by using S- adenosylmethionine (AdoMet) to form N-methylglycine (sarcosine) with the concomitant production of S-adenosylhomocysteine (AdoHcy). Possible crucial role in the regulation of tissue concentration of AdoMet and of metabolism of methionine. Defects in GNMT are the cause of glycine N- methyltransferase deficiency (GNMT deficiency); also known as hypermethioninemia. The only clinical abnormalities in patients with this deficiency are mild hepatomegaly and chronic elevation of serum transaminases. Belongs to the class I-like SAM-binding methyltransferase superfamily. Glycine N-methyltransferase family.
Protein type: Amino Acid Metabolism - glycine, serine and threonine; EC 2.1.1.20; Methyltransferase
Chromosomal Location of Human Ortholog: 6p12
Cellular Component: cytoplasm; cytosol
Molecular Function: glycine binding; glycine N-methyltransferase activity; protein binding
Biological Process: glyoxylate metabolic process; protein homotetramerization; S-adenosylmethionine metabolic process
Disease: Glycine N-methyltransferase Deficiency
Precautions
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Disclaimer
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