Product Name
Actin-related protein 2/3 complex subunit 2 (ARPC2), Recombinant Protein
Full Product Name
Recombinant Bovine Actin-related protein 2/3 complex subunit 2 (ARPC2)
Product Gene Name
ARPC2 recombinant protein
[Similar Products]
Product Synonym Gene Name
ARPC2[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-300aa, full length protein
Sequence
MILLEVNNRI IEETLALKFE NAAAGNKPEA VEVTFADFDG VLYHISNPNG DKTKVMVSIS LKFYKELQAH GADELLKRVY GSYLVNPESG YNVSLLYDLE NLPASKDSIV HQAGMLKRNC FASVFEKYFQ FQEEGKEGEN RAVIHYRDDE TMYVESKKDR VTVVFSTVFK DDDDVVIGKV FMQEFKEGRR ASHTAPQVLF SHREPPLELK DTDAAVGDNI GYITFVLFPR HTNASARDNT INLIHTFRDY LHYHIKCSKA YIHTRMRAKT SDFLKVLNRA RPDAEKKEMK TITGKTFSSR
3D Structure
ModBase 3D Structure for Q3MHR7
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of ARPC2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
ARPC2 recombinant protein
This gene encodes one of seven subunits of the human Arp2
3 protein complex. The Arp2
3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of This protein, the p34 subunit, has yet to be determined. Two alternatively spliced variants have been characterized to date. Additional alternatively spliced variants have been described but their full length nature has not been determined.
NCBI/Uniprot data below describe general gene information for ARPC2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001029885.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001034713.2
[Other Products]
UniProt Primary Accession #
Q3MHR7
[Other Products]
UniProt Related Accession #
Q3MHR7[Other Products]
Molecular Weight
34,349 Da
NCBI Official Full Name
actin-related protein 2/3 complex subunit 2
NCBI Official Symbol
ARPC2 [Similar Products]
NCBI Protein Information
actin-related protein 2/3 complex subunit 2
UniProt Protein Name
Actin-related protein 2/3 complex subunit 2
UniProt Synonym Protein Names
Arp2/3 complex 34 kDa subunit; p34-ARC
UniProt Gene Name
ARPC2 [Similar Products]
UniProt Synonym Gene Names
p34-ARC [Similar Products]
UniProt Comments for ARPC2
Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament ().
Research Articles on ARPC2
1. The GMF-Arp2 interface reveals how the ADF-H actin-binding domain in GMF is exploited to specifically recognize Arp2/3 complex and not actin.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.