ARPC2, Protein

For Research Use Only. Not for use in diagnostic procedures.

Chromosome: 2; NC_000002.11 (219081817..219119071). Location: 2q36.1

Highly Purified
Highly Purified

Supplied as a lyophilized powder in PBS.

May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Small volumes of ARPC2 protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

C-EMKTITGKTFSSR, C Terminus

Molecular Biology; MB-Actin Related Proteins

ELISA (EL/EIA)

Suitable for use in Peptide ELISA.

34,333 Da[Similar Products]

actin related protein 2/3 complex, subunit 2, 34kDa

actin-related protein 2/3 complex subunit 2; arp2/3 complex 34 kDa subunit; ARP2/3 protein complex subunit 34

Actin-related protein 2/3 complex subunit 2

ARC34; p34-ARC  [Similar Products]

ARPC2_HUMAN

This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p34 subunit, has yet to be determined. Two alternatively spliced variants have been characterized to date. Additional alternatively spliced variants have been described but their full length nature has not been determined. [provided by RefSeq, Jul 2008]

ARPC2: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament. Belongs to the ARPC2 family.

Protein type: Motility/polarity/chemotaxis; Actin-binding; Cytoskeletal

Chromosomal Location of Human Ortholog: 2q36.1

Cellular Component: Golgi apparatus; Arp2/3 protein complex; neuron projection; focal adhesion; leading edge; cytoplasm; plasma membrane; synapse; cytosol; endosome; actin cytoskeleton

Molecular Function: actin filament binding; protein binding; structural constituent of cytoskeleton; kinesin binding

Biological Process: axon guidance; ephrin receptor signaling pathway; innate immune response; cell motility

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