CD7, Monoclonal Antibody

For Research Use Only. Not for use in diagnostic procedures.

Monoclonal

IgG2a

LT7

Mouse

Biotin
Purified IgG conjugated to Biotin - liquid

IgG concentration 0.1mg/ml (lot specific)

Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from the date of despatch.

Small volumes of anti-CD7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Mouse anti Human CD7 antibody, clone LT7 recognizes the human T-cell antigen CD7, also known as TP41 or CD7. CD7 is a single chain cell surface glycoprotein of 40kD, expressed by T cells, NK cells and thymocytes. CD7 is also expressed by tumor cells in some cases of acute myeloid leukaemia.

Flow cytometry (FC/FACS)

Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul.
Flow Cytometry: Maximum Dilution: Neat

Staining of human peripheral blood lymphocytes with Mouse anti Human CD7:Biotin

Immunoperoxidase staining of a human tonsil cryosection with Mouse anti Human CD7 antibody, clone CT7 (MBS212052) followed by Histar Detection system. Medium power

Staining of human peripheral blood lymphocytes with Mouse anti Human CD7: FITC (MBS210630)

Immunoperoxidase staining of a human tonsil cryosection with Mouse anti Human CD7 antibody, clone CT7 (MBS212052) followed by Histar Detection system. High power

Immunoperoxidase staining of a human tonsil cryosection with Mouse anti Human CD7 antibody, clone CT7 (MBS212052) followed by Histar Detection system. Medium power

Immunoperoxidase staining of a human tonsil cryosection with Mouse anti Human CD7 antibody, clone CT7 (MBS212052) followed by Histar Detection system. Low power

25,409 Da

CD7 molecule

T-cell antigen CD7; CD7 antigen (p41); T-cell leukemia antigen; T-cell surface antigen Leu-9; p41 protein

T-cell antigen CD7

CD7_HUMAN

This gene encodes a transmembrane protein which is a member of the immunoglobulin superfamily. This protein is found on thymocytes and mature T cells. It plays an essential role in T-cell interactions and also in T-cell/B-cell interaction during early lymphoid development. [provided by RefSeq, Jul 2008]

CD7: Not yet known.

Protein type: Membrane protein, integral; Immunoglobulin superfamily

Chromosomal Location of Human Ortholog: 17q25.2-q25.3

Cellular Component: membrane; integral to membrane; plasma membrane

Molecular Function: receptor activity

Biological Process: T cell activation; homeostasis of number of cells within a tissue; immune response; transmembrane receptor protein tyrosine kinase signaling pathway

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