Full Product Name
Purified Anti-Human CD7 Monoclonal Antibody
Product Synonym Names
Human CD7; T-cell antigen CD7; CD7; GP40; T-cell leukemia antigen; T-cell surface antigen Leu-9; TP41; TP41
Product Gene Name
anti-CD7 antibody
[Similar Products]
Matching Pairs
Antibody: CD7 Clone #124-1D1 (MBS2553857)
Isotype Control: IgG1, kappa Clone #MOPC-21 (MBS2557744)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P09564
Form/Format
Liquid; PBS with 0.05% Proclin300, 1% BSA
Cellular Localization
Membrane
Preparation and Storage
Store at 2-8 degree C. Protected from prolonged exposure to light.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-CD7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CD7 antibody
CD7 is a 40 kD type I transmembrane glycoprotein also known as gp40. It is a member of the immunoglobulin superfamily found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly). CD7 is also expressed on acute lymphocytic leukemia (ALL) and some acute myeloid leukemia (AML) cells. CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 costimulation can induce cytokine secretion and modulate cellular adhesion.
Applications Tested/Suitable for anti-CD7 antibody
Flow Cytometry (FC/FACS)
Application Notes for anti-CD7 antibody
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is <=1.0 ug per 10e6 cells in 100 ul volume or 100 ul of whole blood.
NCBI/Uniprot data below describe general gene information for CD7. It may not necessarily be applicable to this product.
NCBI Accession #
NP_006128.1
[Other Products]
NCBI GenBank Nucleotide #
NM_006137.7
[Other Products]
UniProt Primary Accession #
P09564
[Other Products]
UniProt Related Accession #
P09564[Other Products]
Molecular Weight
25,409 Da
NCBI Official Full Name
T-cell antigen CD7
NCBI Official Synonym Full Names
CD7 molecule
NCBI Official Symbol
CD7 [Similar Products]
NCBI Official Synonym Symbols
GP40; TP41; Tp40; LEU-9
[Similar Products]
NCBI Protein Information
T-cell antigen CD7
UniProt Protein Name
T-cell antigen CD7
UniProt Synonym Protein Names
GP40; T-cell leukemia antigen; T-cell surface antigen Leu-9; TP41; CD_antigen: CD7
Protein Family
CD70 antigen
UniProt Gene Name
CD7 [Similar Products]
NCBI Summary for CD7
This gene encodes a transmembrane protein which is a member of the immunoglobulin superfamily. This protein is found on thymocytes and mature T cells. It plays an essential role in T-cell interactions and also in T-cell/B-cell interaction during early lymphoid development. [provided by RefSeq, Jul 2008]
UniProt Comments for CD7
Not yet known.
Product References and Citations for anti-CD7 antibody
1. Barclay N, et al. 1993. The Leucocyte Antigen FactsBook. Academic Press Inc. San Diego. 2. Stillwell R, et al. 2001. Immunol. Res. 24:31. 3. Rabinowich H, et al. 1994. J. Immunol. 152:517.
Research Articles on CD7
1. in acute myeloid leukemia patients the association of CD7 positivity and FLT3 positivity was found to be significant
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
