Full Product Name
SPEG Polyclonal Antibody
Product Synonym Names
Striated muscle preferentially expressed protein kinase; EC 2.7.11.1; Aortic preferentially expressed protein 1; APEG-1; SPEG; APEG1; KIAA1297
Product Gene Name
anti-SPEG antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q15772
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Preparation and Storage
Store at-20 degree C for 1 year.
Other Notes
Small volumes of anti-SPEG antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-SPEG antibody
Immunohistochemistry (IHC) Paraffin
Application Notes for anti-SPEG antibody
IHC-p: 1:50-300
NCBI/Uniprot data below describe general gene information for SPEG. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001166947.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001173476.1
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UniProt Primary Accession #
Q15772
[Other Products]
UniProt Secondary Accession #
Q27J74; Q695L1; Q6FGA6; Q6ZQW1; Q6ZTL8; Q9P2P9; A8K0G6; A8MRU0[Other Products]
UniProt Related Accession #
Q15772[Other Products]
NCBI Official Full Name
striated muscle preferentially expressed protein kinase isoform 4
NCBI Official Synonym Full Names
SPEG complex locus
NCBI Official Symbol
SPEG [Similar Products]
NCBI Official Synonym Symbols
BPEG; CNM5; APEG1; APEG-1; SPEGbeta; SPEGalpha
[Similar Products]
NCBI Protein Information
striated muscle preferentially expressed protein kinase
UniProt Protein Name
Striated muscle preferentially expressed protein kinase
UniProt Synonym Protein Names
Aortic preferentially expressed protein 1; APEG-1
Protein Family
Striated muscle preferentially expressed protein kinase
UniProt Gene Name
SPEG [Similar Products]
UniProt Synonym Gene Names
APEG1; KIAA1297; APEG-1 [Similar Products]
NCBI Summary for SPEG
This gene encodes a protein with similarity to members of the myosin light chain kinase family. This protein family is required for myocyte cytoskeletal development. Along with the desmin gene, expression of this gene may be controlled by the desmin locus control region. Mutations in this gene are associated with centronuclear myopathy 5. [provided by RefSeq, Jun 2016]
UniProt Comments for SPEG
Isoform 3 may have a role in regulating the growth and differentiation of arterial smooth muscle cells.
Research Articles on SPEG
1. SPEG is present in cardiac muscle, where it plays a critical role; therefore, individuals with SPEG mutations additionally present with dilated cardiomyopathy.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
