Product Name
C-X-C chemokine receptor type 5 (Cxcr5), Recombinant Protein
Full Product Name
Recombinant Rat C-X-C chemokine receptor type 5 (Cxcr5)
Product Synonym Names
Recombinant C-X-C chemokine receptor type 5 (Cxcr5); C-X-C chemokine receptor type 5; CXC-R5; CXCR-5; Burkitt lymphoma receptor 1 homolog Neurolymphatic receptor; NLR CD_antigen= CD185
Product Gene Name
Cxcr5 recombinant protein
[Similar Products]
Product Synonym Gene Name
Cxcr5; Blr1[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
MNSPISLDMG AITYNMDDLY KELAIYSNST EIPLQDSIFC STEEGPLLTS FKTIFMPVAY SLIFLLGMMG NILVLVILER HRHTRSSTET FLFHLAVADL LLVFILPFAV AEGSVGWVLG TFLCKTVIAL HKINFYCSSL LLACIAVDRY LAIVHAVHAY RRRRLLSIHI TCSTIWLAGF LFALPELLFA KVVQPHNNES LPQCIFSQEN EAETRAWFAS RFLYHTGGFL LPMLVMAWCY VGVVHRLLQA QRRPQRQKAV RVAILVTSIF LLCWSPYHIV IFLDTLERLK AVNSSCELSG YLSVAITLCE FLGLAHCCLN PMLYTFAGVK FRSDLSRLLT KLGCAGPASL CQLFPGWRKS SLSESENATS LTTF
Chromosome Location
Chromosome: 8; NC_005107.3 (47455500..47468884, complement). Location: 8q22
3D Structure
ModBase 3D Structure for P34997
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>=90% (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Rattus norvegicus (Rat)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Cxcr5 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for Cxcr5. It may not necessarily be applicable to this product.
NCBI Accession #
NP_445755.1
[Other Products]
NCBI GenBank Nucleotide #
NM_053303.1
[Other Products]
UniProt Primary Accession #
P34997
[Other Products]
UniProt Related Accession #
P34997[Other Products]
Molecular Weight
42,013 Da[Similar Products]
NCBI Official Full Name
C-X-C chemokine receptor type 5
NCBI Official Synonym Full Names
chemokine (C-X-C motif) receptor 5
NCBI Official Symbol
Cxcr5 [Similar Products]
NCBI Official Synonym Symbols
NLR; Blr1
[Similar Products]
NCBI Protein Information
C-X-C chemokine receptor type 5; CXC-R5; CXCR-5; neurolymphatic receptor; burkitt lymphoma receptor 1 homolog; chemochine (C-X-C motif) receptor 5
UniProt Protein Name
C-X-C chemokine receptor type 5
UniProt Synonym Protein Names
Burkitt lymphoma receptor 1 homolog; Neurolymphatic receptor
Protein Family
C-X-C chemokine receptor
UniProt Gene Name
Cxcr5 [Similar Products]
UniProt Synonym Gene Names
Blr1; CXC-R5; CXCR-5; NLR [Similar Products]
UniProt Entry Name
CXCR5_RAT
NCBI Summary for Cxcr5
G-protein coupled receptor that may play a role in the nervous and immune systems [RGD, Feb 2006]
UniProt Comments for Cxcr5
CXCR5: Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation. Belongs to the G-protein coupled receptor 1 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR
Cellular Component: integral to membrane; plasma membrane; external side of plasma membrane
Molecular Function: C-X-C chemokine receptor activity
Biological Process: positive regulation of cytokinesis; G-protein coupled receptor protein signaling pathway; B cell activation; immune response; chemotaxis; lymph node development
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.