Full Product Name
CD23 antibody
Product Synonym Names
Monoclonal CD23; Anti-CD23; CD-23; FCeRII; CD23; Fc-epsilon-RII; Lymphocyte IgE receptor; BLAST-2; CD 23; CD23 antigen
Product Gene Name
anti-CD23 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q63097
Species Reactivity
Murine
Form/Format
Supplied as a liquid in 100mM BBS, pH 8.2.
Concentration
0.5 mg/ml (lot specific)
Biological Significance
CD23, also known as Fc epsilon RII, or FceRII, is the "low-affinity" receptor for IgE, an antibody isotype involved in allergy and resistance to parasites, and is important in regulation of IgE levels. Unlike many of the antibody receptors, CD23 is a C-type lectin. It is found on mature B cells, activated macrophages, eosinophils, follicular dendritic cells, and platelets. There are two forms of CD23: CD23a and CD23b. CD23a is present on follicular B cells, whereas CD23b requires IL-4 to be expressed on T-cells, monocytes, Langerhans cells, eosinophils, and macrophages.
Immunogen
CD23 antibody was raised in rat using CD23 low affinity IgE Fc receptor as the immunogen.
Preparation and Storage
Store at 4 degree C.
Other Notes
Small volumes of anti-CD23 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CD23 antibody
Rat monoclonal CD23 antibody
Product Categories/Family for anti-CD23 antibody
Immunology
Applications Tested/Suitable for anti-CD23 antibody
Flow Cytometry (FC/FACS), Immunoprecipitation (IP)
NCBI/Uniprot data below describe general gene information for CD23. It may not necessarily be applicable to this product.
NCBI Accession #
CAA51981.1
[Other Products]
UniProt Primary Accession #
Q63097
[Other Products]
Molecular Weight
35,126 Da
NCBI Official Full Name
CD23
NCBI Official Synonym Full Names
Fc fragment of IgE, low affinity II, receptor for (CD23)
NCBI Official Symbol
Fcer2 [Similar Products]
NCBI Official Synonym Symbols
CD23; Fcer2a
[Similar Products]
NCBI Protein Information
low affinity immunoglobulin epsilon Fc receptor
UniProt Protein Name
CD23 protein
UniProt Synonym Protein Names
CD23 protein
UniProt Gene Name
Fcer2 [Similar Products]
UniProt Entry Name
Q63097_RAT
NCBI Summary for CD23
cell surface receptor; binds innumoglobulin (Ig)E and IgA antibodies [RGD, Feb 2006]
Research Articles on CD23
1. Immunohistochemical analyses suggested that the Fcalpha/muR isoform was expressed in the tubular epithelial cells, but not in the glomeruli.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
