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Endocrine Gland Vascular Endothelial Growth Factor, ELISA Kit

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产品名称: Endocrine Gland Vascular Endothelial Growth Factor, ELISA Kit
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简单介绍

Endocrine Gland Vascular Endothelial Growth Factor, ELISA Kit


Endocrine Gland Vascular Endothelial Growth Factor, ELISA Kit  的详细介绍
Product Name

Endocrine Gland Vascular Endothelial Growth Factor (EG-VEGF), ELISA Kit

Full Product Name

Porcine Endocrine Gland Vascular Endothelial Growth Factor ELISA Kit

Product Gene Name

EG-VEGF elisa kit

[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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Request for Current Manual Insert
Request Current Manual
Chromosome Location
Chromosome: 1; NC_000001.10 (110993788..110999976). Location: 1p21
OMIM
606233
3D Structure
ModBase 3D Structure for P58294
Species Reactivity
Porcine
Assay Type
Sandwich
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of EG-VEGF elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for EG-VEGF purchase
MBS024852 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Endocrine Gland Vascular Endothelial Growth Factor (EG-VEGF) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing EG-VEGF. The ELISA analytical biochemical technique of the MBS024852 kit is based on EG-VEGF antibody-EG-VEGF antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect EG-VEGF antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, EG-VEGF. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for EG-VEGF. It may not necessarily be applicable to this product.
NCBI GI #
37182488
NCBI GeneID
84432
NCBI Accession #
AAQ89046.1 [Other Products]
UniProt Primary Accession #
P58294 [Other Products]
UniProt Secondary Accession #
Q5VWD4; Q8TC69[Other Products]
UniProt Related Accession #
P58294[Other Products]
Molecular Weight
11,715 Da
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NCBI Official Full Name
EG-VEGF
NCBI Official Synonym Full Names
prokineticin 1
NCBI Official Symbol
PROK1  [Similar Products]
NCBI Official Synonym Symbols
PK1; PRK1; EGVEGF
  [Similar Products]
NCBI Protein Information
prokineticin-1; EG-VEGF; mambakine; black mamba toxin-related protein; endocrine-gland-derived vascular endothelial growth factor
UniProt Protein Name
Prokineticin-1
UniProt Synonym Protein Names
Endocrine-gland-derived vascular endothelial growth factor; EG-VEGF; Mambakine
UniProt Gene Name
PROK1  [Similar Products]
UniProt Synonym Gene Names
EG-VEGF  [Similar Products]
UniProt Entry Name
PROK1_HUMAN
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NCBI Summary for EG-VEGF
The protein encoded by this gene induces proliferation, migration, and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. It has little or no effect on a variety of other endothelial and non-endothelial cell types. Its expression is restricted to the steroidogenic glands (ovary, testis, adrenal, and placenta), is induced by hypoxia, and often complementary to the expression of vascular endothelial growth factor (VEGF), suggesting that these molecules function in a coordinated manner. [provided by RefSeq, Sep 2011]
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UniProt Comments for EG-VEGF
PROK1: Potently contracts gastrointestinal (GI) smooth muscle. Induces proliferation, migration and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. Has little or no effect on a variety of other endothelial and non-endothelial cell types. Induces proliferation and differentiation, but not migration, of enteric neural crest cells. Directly influences neuroblastoma progression by promoting the proliferation and migration of neuroblastoma cells. Positively regulates PTGS2 expression and prostaglandin synthesis. May play a role in placentation. May play a role in normal and pathological testis angiogenesis. Belongs to the AVIT (prokineticin) family.

Protein type: Cell cycle regulation; Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 1p21

Cellular Component: extracellular region

Molecular Function: growth factor activity

Biological Process: activation of MAPK activity; positive regulation of cell division; positive regulation of cell proliferation; angiogenesis; regulation of angiogenesis
Research Articles on EG-VEGF
1. EG-VEGF as a new placental growth factor acting during the first trimester of pregnancy, established its mechanism of action, and provide evidence for its deregulation in FGR.
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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