Full Product Name
EXT2 Antibody - C-terminal region
Product Gene Name
anti-EXT2 antibody
[Similar Products]
Product Synonym Gene Name
EXT2;[Similar Products]
Antibody/Peptide Pairs
EXT2 peptide (MBS3244328) is used for blocking the activity of EXT2 antibody (MBS3219448)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Synthetic peptide located within the following region: LTYDRVESLF RVITEVSKVP SLSKLLVVWN NQNKNPPEDS LWPKIRVPLK
3D Structure
ModBase 3D Structure for Q93063
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human EXT2
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-EXT2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-EXT2 antibody
This is a rabbit polyclonal antibody against EXT2. It was validated on Western Blot
Target Description: This gene encodes one of two glycosyltransferases involved in the chain elongation step of heparan sulfate biosynthesis. Mutations in this gene cause the type II form of multiple exostoses. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Product Categories/Family for anti-EXT2 antibody
Polyclonal; Signal Proteins; Cell Cycle Proteins; Membrane Protein; Cell Biology; Membrane & Traffic; Disease Related;
Applications Tested/Suitable for anti-EXT2 antibody
Western Blot (WB)
Western Blot (WB) of anti-EXT2 antibody
Host: Rabbit
Target Name: EXT2
Sample Type: Placenta lysates
Antibody Dilution: 1.0ug/ml
NCBI/Uniprot data below describe general gene information for EXT2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_997005
[Other Products]
NCBI GenBank Nucleotide #
NM_207122.1
[Other Products]
UniProt Primary Accession #
Q93063
[Other Products]
UniProt Related Accession #
Q93063[Other Products]
NCBI Official Full Name
exostosin-2 isoform 2
NCBI Official Synonym Full Names
exostosin glycosyltransferase 2
NCBI Official Symbol
EXT2 [Similar Products]
NCBI Official Synonym Symbols
SOTV; SSMS
[Similar Products]
NCBI Protein Information
exostosin-2
UniProt Protein Name
Exostosin-2
UniProt Synonym Protein Names
Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase; Multiple exostoses protein 2; Putative tumor suppressor protein EXT2
UniProt Gene Name
EXT2 [Similar Products]
UniProt Entry Name
EXT2_HUMAN
NCBI Summary for EXT2
This gene encodes one of two glycosyltransferases involved in the chain elongation step of heparan sulfate biosynthesis. Mutations in this gene cause the type II form of multiple exostoses. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008]
Research Articles on EXT2
1. The present study identified pathogenic mutations in 93% (68/73) of unrelated hereditary multiple osteochondromasprobands from 73 pedigrees. Mutations in EXT1 and EXT2 were identified in 53% (39/73) and 40% (29/73) of families.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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