Product Name
Solute Carrier Family 12 Member 3 (SLC12A3), ELISA Kit
Full Product Name
Hamster Solute Carrier Family 12 Member 3 (SLC12A3) ELISA Kit
Product Gene Name
SLC12A3 elisa kit
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
Request Current Manual
3D Structure
ModBase 3D Structure for P55018
Species Reactivity
Hamster
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of SLC12A3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for SLC12A3 purchase
MBS9900881 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Solute Carrier Family 12 Member 3 (SLC12A3) ELISA Kit target analytes in
biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing SLC12A3. The ELISA analytical biochemical technique of the MBS9900881 kit is based on SLC12A3 antibody-SLC12A3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect SLC12A3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, SLC12A3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
NCBI/Uniprot data below describe general gene information for SLC12A3. It may not necessarily be applicable to this product.
NCBI Accession #
NP_062218.3
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NCBI GenBank Nucleotide #
NM_019345.3
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UniProt Primary Accession #
P55018
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UniProt Related Accession #
P55018[Other Products]
Molecular Weight
110,554 Da
NCBI Official Full Name
solute carrier family 12 member 3
NCBI Official Synonym Full Names
solute carrier family 12 member 3
NCBI Official Symbol
Slc12a3 [Similar Products]
NCBI Official Synonym Symbols
NCC; TSC
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NCBI Protein Information
solute carrier family 12 member 3
UniProt Protein Name
Solute carrier family 12 member 3
UniProt Synonym Protein Names
Na-Cl symporter; Thiazide-sensitive sodium-chloride cotransporter
Protein Family
Solute carrier family
UniProt Gene Name
Slc12a3 [Similar Products]
UniProt Synonym Gene Names
Tsc [Similar Products]
NCBI Summary for SLC12A3
mediates thiazide-sensitive cotransport of sodium and chloride; may play a role in the metabolism of NaCl and other electrolytes [RGD, Feb 2006]
UniProt Comments for SLC12A3
NCCT: Key mediator of sodium and chloride reabsorption in this nephron segment, accounting for a significant fraction of renal sodium reabsorption. Interacts with KLHL3. Predominant in kidney. Activated by WNK3. Belongs to the SLC12A transporter family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family
Chromosomal Location of Human Ortholog: 19p13-p12
Cellular Component: apical plasma membrane; cytosol; integral component of membrane; plasma membrane; vesicle
Molecular Function: cation:chloride symporter activity; enzyme binding; sodium ion transmembrane transporter activity; sodium:chloride symporter activity; transporter activity
Biological Process: chloride transport; sodium ion transport
Research Articles on SLC12A3
1. Kidneys respond acutely to hyperkalemic challenges by decreasing the activity of NCC while increasing that of ENaC.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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