Product Name
BTNL2, cDNA Clone
Popular Item
Full Product Name
BTNL2 cDNA Clone
Product Gene Name
BTNL2 cdna clone
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
ATGGTGGATT TTCCAGGCTA CAATCTGTCT GGTGCAGTCG CCTCCTTCCT ATTCATCCTG CTGACAATGA AGCAGTCAGA GAAACTCCAG ACTGAGCTGG CTTCTTTAAA AGTGAATGGA CCTTCCCAGC CCATCCTCGT CAGAGTGGGA GAAGATATAC AGCTAACCTG TTACCTGTCC CCCAAGGCGA ATGCACAGAG CATGGAGGTG AGGTGGGACC GATCCCACCG TTACCCTGCT GTGCATGTGT ATATGGATGG GGACCATGTG GCTGGAGAGC AGATGGCAGA GTACAGAGGG AGGACTGTGC TGGTGAGTGA CGCCATTGAC GAGGGCAGAC TGACCCTGCA GATACTCAGT GCCAGACCTT CGGACGACGG GCAGTACCGC TGCCTTTTTG AAAAAGATGA TGTCTACCAA GAGGCCAGTT TGGATCTGAA GGTGGTAGGT CTGGGTTCTT CCCCACTGAT CACTGTGGAG GGGCAAGAAG ATGGAGAAAT GCAGCCGATG TGCTCTTCAG ATGGGTGGTT CCCACAGCCC CACGTGCCAT GGAGGGACAT GGAAGGAAAG ACGATACCAT CATCTTCCCA GGCCCTGACT CAAGGCAGCC ACGGGCTGTT CCACGTGCAG ACATTGCTAA GGGTCACAAA CATCTCCGCT GTGGACGTCA CTTGTTCCAT CAGCATCCCC TTTTTGGGCG AGGAGAAAAT CGCAACTTTT TCTCTCTCAG GTTGGTGA
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of BTNL2 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for BTNL2. It may not necessarily be applicable to this product.
NCBI Accession #
BC127642
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UniProt Secondary Accession #
O98261; Q08E96; Q58R22; Q58R23; Q5JYF9; Q5MP42; Q5MP43; Q5RIF8; A0PJV5; B0UYW9; B0V0N6[Other Products]
UniProt Related Accession #
Q9UIR0[Other Products]
Molecular Weight
28,660 Da
NCBI Official Full Name
Homo sapiens butyrophilin-like 2 (MHC class II associated), mRNA
NCBI Official Synonym Full Names
butyrophilin like 2
NCBI Official Symbol
BTNL2 [Similar Products]
NCBI Official Synonym Symbols
SS2; BTN7; BTL-II; HSBLMHC1
[Similar Products]
NCBI Protein Information
butyrophilin-like protein 2
UniProt Protein Name
Butyrophilin-like protein 2
Protein Family
Butyrophilin-like protein
UniProt Gene Name
BTNL2 [Similar Products]
UniProt Synonym Gene Names
BTL-II [Similar Products]
UniProt Entry Name
BTNL2_HUMAN
UniProt Comments for BTNL2
BTNL2: Negative regulator of T-cell proliferation. Genetic variation in BTNL2 is a cause of susceptibility to sarcoidosis type 2 (SS2). Sarcoidosis is an idiopathic, systemic, inflammatory disease characterized by the formation of immune granulomas in involved organs. Granulomas predominantly invade the lungs and the lymphatic system, but also skin, liver, spleen, eyes and other organs may be involved. A nucleotide transition affecting a splice donor site results in the use of an alternative splice site and the production of isoform 3. Individuals expressing isoform 3 have a higher risk for sarcoidosis. Belongs to the immunoglobulin superfamily. BTN/MOG family. 6 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 6p21.3
Disease: Sarcoidosis, Susceptibility To, 2
Research Articles on BTNL2
1. Results confirm the association of BTNL2 rs2076530SNP with the susceptibility to develop sarcoidosis, but not with an increased risk of cancer in these patients.
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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