Product Name
Neuron-specific vesicular protein calcyon (CALY), Recombinant Protein
Full Product Name
Recombinant Human Neuron-specific vesicular protein calcyon (CALY), partial
Product Gene Name
CALY recombinant protein
[Similar Products]
Product Synonym Gene Name
CALY[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
MVKLGCSFSG KPGKDPGDQD GAAMDSVPLI SPLDISQLQP PLPDQVVIKT QTEYQLSSPD QQNFPDLEGQ RLNCSHPEEG RRLPTAR
3D Structure
ModBase 3D Structure for Q9NYX4
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of CALY recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
CALY recombinant protein
This protein is a type II single transmembrane protein. It is required for maximal stimulated calcium release after stimulation of purinergic or muscarinic but not beta-adrenergic receptors. The encoded protein interacts with D1 dopamine receptor and may interact with other DA receptor subtypes and
or GPCRs.
NCBI/Uniprot data below describe general gene information for CALY. It may not necessarily be applicable to this product.
NCBI Accession #
NP_056537.1
[Other Products]
NCBI GenBank Nucleotide #
NM_015722.3
[Other Products]
UniProt Primary Accession #
Q9NYX4
[Other Products]
UniProt Secondary Accession #
Q5VWX3; Q5VWY5; Q5VWY6[Other Products]
UniProt Related Accession #
Q9NYX4[Other Products]
Molecular Weight
17,547 Da
NCBI Official Full Name
neuron-specific vesicular protein calcyon isoform 1
NCBI Official Synonym Full Names
calcyon neuron specific vesicular protein
NCBI Official Symbol
CALY [Similar Products]
NCBI Official Synonym Symbols
NSG3; DRD1IP
[Similar Products]
NCBI Protein Information
neuron-specific vesicular protein calcyon
UniProt Protein Name
Neuron-specific vesicular protein calcyon
Protein Family
Neuron-specific vesicular protein calcyon
UniProt Gene Name
CALY [Similar Products]
UniProt Synonym Gene Names
DRD1IP [Similar Products]
NCBI Summary for CALY
The protein encoded by this gene is a type II single transmembrane protein. It is required for maximal stimulated calcium release after stimulation of purinergic or muscarinic but not beta-adrenergic receptors. The encoded protein interacts with D1 dopamine receptor and may interact with other DA receptor subtypes and/or GPCRs. [provided by RefSeq, Jul 2008]
UniProt Comments for CALY
Interacts with clathrin light chain A and stimulates clathrin self-assembly and clathrin-mediated endocytosis.
Research Articles on CALY
1. This review focuses on two closely related, neuron-enriched endosomal proteins: NEEP21 and Calcyon which perform distinct roles in regulating receptor endocytosis, recycling, and degradation--{REVIEW}
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
