Product Name
BF1 / FOXG1, Polyclonal Antibody
Full Product Name
Anti-BF1 / FOXG1 Antibody (Internal) IHC-plus
Product Synonym Names
Rabbit Polyclonal to Human BF1 / FOXG1; Human BF1 / FOXG1; BF2; Brain factor 1; BF-2; FKHL1; FKHL2; Forkhead box G1A; Forkhead box protein G1; Forkhead box protein G1A; Forkhead-related protein FKHL1; Forkhead-related protein FKHL2; FOXG1A; FOXG1B; FOXG1C; Forkhead box protein G1B
Product Gene Name
anti-BF1 / FOXG1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P55316
Species Reactivity
Mouse, Rat, Human
Specificity
FOXG1 antibody is human, mouse and rat reactive.
Purity/Purification
Immunoaffinity purified
Form/Format
PBS, 0.02% sodium azide.
Concentration
1 mg/ml (lot specific)
Immunogen
BF1 / FOXG1 antibody was raised against fOXG1 antibody was raised against an 18 amino acid peptide near the center of human FOXG1.
Immunogen Description
FOXG1 antibody was raised against an 18 amino acid peptide near the center of human FOXG1.
Immunogen Type
Synthetic peptide
Antigen Modification
Internal
Preparation and Storage
Long term: -20 degree C
Short term: 4 degree C
Avoid repeat freeze-thaw cycles
Other Notes
Small volumes of anti-BF1 / FOXG1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-BF1 / FOXG1 antibody
FOXG1 Antibody, BF1 Antibody, BF2 Antibody, Brain factor 1 Antibody, BF-2 Antibody, FKHL1 Antibody, FKHL2 Antibody, Forkhead box G1A Antibody, Forkhead box protein G1 Antibody, Forkhead box protein G1A Antibody, Forkhead-related protein FKHL1 Antibody, Forkhead-related protein FKHL2 Antibody, FOXG1A Antibody, FOXG1B Antibody, FOXG1C Antibody, Forkhead box protein G1B Antibody, Forkhead-like 2 Antibody, Forkhead-like 4 Antibody, HBF2 Antibody, HBF-1 Antibody, HFK1 Antibody, FKH2 Antibody, FKHL3 Antibody, FKHL4 Antibody, Forkhead box G1 Antibody, Forkhead box G1B Antibody, Forkhead box G1C Antibody, Forkhead-like 1 Antibody, Forkhead-related protein FKHL3 Antibody, HBF-3 Antibody, HBF-G2 Antibody, HFK3 Antibody, Transcription factor bf-2 Antibody, Oncogene QIN Antibody, QIN Antibody, BF-1 Antibody, Brain factor 2 Antibody, FHKL3 Antibody, Forkhead box protein G1C Antibody, Forkhead-like 3 Antibody, HBF-2 Antibody, HFK2 Antibody, KHL2 Antibody Description: This gene belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in the development of the brain and telencephalon.
Applications Tested/Suitable for anti-BF1 / FOXG1 antibody
Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), Western Blot (WB), ELISA (EIA)
Application Notes for anti-BF1 / FOXG1 antibody
IF (20 ug/ml)
IHC-P (10 ug/ml)
WB (1 - 2 ug/ml)
Immunohistochemistry (IHC) of anti-BF1 / FOXG1 antibody
Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE)

Immunofluorescence (IF) of anti-BF1 / FOXG1 antibody
Immunofluorescence of FOXG1 in mouse brain tissue with FOXG1 antibody at 20 ug/ml.

NCBI/Uniprot data below describe general gene information for BF1 / FOXG1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_005240.3
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NCBI GenBank Nucleotide #
NM_005249.4
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UniProt Primary Accession #
P55316
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UniProt Secondary Accession #
P55315; Q14488; Q86XT7; A6NFY2[Other Products]
UniProt Related Accession #
P55316[Other Products]
Molecular Weight
52,352 Da
NCBI Official Full Name
forkhead box protein G1
NCBI Official Synonym Full Names
forkhead box G1
NCBI Official Symbol
FOXG1 [Similar Products]
NCBI Official Synonym Symbols
BF1; BF2; QIN; FKH2; HBF2; HFK1; HFK2; HFK3; KHL2; FHKL3; FKHL1; FKHL2; FKHL3; FKHL4; HBF-1; HBF-2; HBF-3; FOXG1A; FOXG1B; FOXG1C; HBF-G2
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NCBI Protein Information
forkhead box protein G1
UniProt Protein Name
Forkhead box protein G1
UniProt Synonym Protein Names
Brain factor 1; BF-1; BF1; Brain factor 2; BF-2; BF2; hBF-2; Forkhead box protein G1A; Forkhead box protein G1B; Forkhead box protein G1C; Forkhead-related protein FKHL1; HFK1; Forkhead-related protein FKHL2; HFK2; Forkhead-related protein FKHL3; HFK3
UniProt Gene Name
FOXG1 [Similar Products]
UniProt Synonym Gene Names
FKH2; FKHL1; FKHL2; FKHL3; FKHL4; FOXG1A; FOXG1B; FOXG1C; BF-1; BF1; BF-2; BF2; hBF-2; HFK1; HFK2; HFK3 [Similar Products]
UniProt Entry Name
FOXG1_HUMAN
NCBI Summary for BF1 / FOXG1
This locus encodes a member of the forked-head transcription factor family. The encoded protein, which functions as a repressor, may play a role in brain development. Mutations at this locus have been associated with Rett syndrome. [provided by RefSeq, Feb 2012]
UniProt Comments for BF1 / FOXG1
FOXG1: Transcription repression factor which plays an important role in the establishment of the regional subdivision of the developing brain and in the development of the telencephalon. Interacts with KDM5B. Expression is restricted to the neurons of the developing telencephalon.
Protein type: Transcription factor; DNA-binding; Nuclear receptor co-regulator
Chromosomal Location of Human Ortholog: 14q13
Cellular Component: nucleus
Molecular Function: DNA binding; protein binding; sequence-specific DNA binding
Biological Process: aging; anatomical structure morphogenesis; brain development; cell differentiation; negative regulation of transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent
Disease: Rett Syndrome, Congenital Variant
Research Articles on BF1 / FOXG1
1. EGFR mutations remodel the activated enhancer landscape of glioblastoma multiforme, promoting tumorigenesis through a SOX9 and FOXG1-dependent transcriptional regulatory network in vitro and in vivo.
Precautions
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Disclaimer
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