Full Product Name
FOXG1, ID (FOXG1, FKH2, FKHL1, FKHL2, FKHL3, FKHL4, FOXG1A, FOXG1B, FOXG1C, Forkhead box protein G1, Brain factor 1, Brain factor 2, Forkhead box protein G1A, Forkhead box protein G1B, Forkhead box protein G1C, Forkhead-related protein FKHL1, Forkhead-rel
Product Synonym Names
Anti -FOXG1, ID (FOXG1, FKH2, FKHL1, FKHL2, FKHL3, FKHL4, FOXG1A, FOXG1B, FOXG1C, Forkhead box protein G1, Brain factor 1, Brain factor 2, Forkhead box protein G1A, Forkhead box protein G1B, Forkhead box protein G1C, Forkhead-related protein FKHL1, Forkhead-rel
Product Gene Name
anti-FOXG1 antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
Chromosome: 14; NC_000014.8 (29236278..29239483). Location: 14q13
3D Structure
ModBase 3D Structure for P55316
Species Reactivity
Human, Mouse
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Immunogen
FOXG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 231~261 amino acids from the Central region of human FOXG1.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Other Notes
Small volumes of anti-FOXG1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-FOXG1 antibody
This gene belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in the development of the brain and telencephalon.
Product Categories/Family for anti-FOXG1 antibody
Antibodies; Abs to Transcription Factors
Applications Tested/Suitable for anti-FOXG1 antibody
ELISA (EL/EIA), Western Blot (WB), Flow Cytometry (FC/FACS)
Application Notes for anti-FOXG1 antibody
Suitable for use in Western Blot, Flow Cytometry, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Flow Cytometry: 1:10-50
NCBI/Uniprot data below describe general gene information for FOXG1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_005240.3
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NCBI GenBank Nucleotide #
NM_005249.4
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UniProt Primary Accession #
P55316
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UniProt Secondary Accession #
P55315; Q14488; Q86XT7; A6NFY2[Other Products]
UniProt Related Accession #
P55316[Other Products]
Molecular Weight
52,352 Da[Similar Products]
NCBI Official Full Name
forkhead box protein G1
NCBI Official Synonym Full Names
forkhead box G1
NCBI Official Symbol
FOXG1 [Similar Products]
NCBI Official Synonym Symbols
BF1; BF2; QIN; FKH2; HBF2; HFK1; HFK2; HFK3; KHL2; FHKL3; FKHL1; FKHL2; FKHL3; FKHL4; HBF-1; HBF-2; HBF-3; FOXG1A; FOXG1B; FOXG1C; HBF-G2
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NCBI Protein Information
forkhead box protein G1; oncogene QIN; brain factor 1; brain factor 2; forkhead-like 1; forkhead-like 2; forkhead-like 3; forkhead-like 4
UniProt Protein Name
Forkhead box protein G1
UniProt Synonym Protein Names
Brain factor 1; BF-1; BF1; Brain factor 2; BF-2; BF2; hBF-2; Forkhead box protein G1A; Forkhead box protein G1B; Forkhead box protein G1C; Forkhead-related protein FKHL1; HFK1; Forkhead-related protein FKHL2; HFK2; Forkhead-related protein FKHL3
Protein Family
Forkhead box protein
UniProt Gene Name
FOXG1 [Similar Products]
UniProt Synonym Gene Names
FKH2; FKHL1; FKHL2; FKHL3; FKHL4; FOXG1A; FOXG1B; FOXG1C; BF-1; BF1; BF-2; BF2; hBF-2; HFK1; HFK2; HFK3 [Similar Products]
UniProt Entry Name
FOXG1_HUMAN
NCBI Summary for FOXG1
This locus encodes a member of the forked-head transcription factor family. The encoded protein, which functions as a repressor, may play a role in brain development. Mutations at this locus have been associated with Rett syndrome. [provided by RefSeq, Feb 2012]
UniProt Comments for FOXG1
FOXG1: Transcription repression factor which plays an important role in the establishment of the regional subdivision of the developing brain and in the development of the telencephalon. Interacts with KDM5B. Expression is restricted to the neurons of the developing telencephalon.
Protein type: Transcription factor; DNA-binding; Nuclear receptor co-regulator
Chromosomal Location of Human Ortholog: 14q13
Cellular Component: nucleus
Molecular Function: protein binding; DNA binding; sequence-specific DNA binding; transcription factor activity
Biological Process: transcription, DNA-dependent; brain development; negative regulation of transcription, DNA-dependent; aging
Disease: Rett Syndrome, Congenital Variant
Research Articles on FOXG1
1. In fibroblast cells, a cis-acting regulatory sequence located more than 0.6 Mb away from FOXG1 acts as a silencer at the transcriptional level.
Precautions
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Disclaimer
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