High mobility group protein HMGI-C (HMGA2), ELISA Kit

high mobility group AT-hook 2; BABL; HMGI-C; HMGIC; LIPO; STQTL9; High-mobility group protein HMGI-C|high-mobility group (nonhistone chromosomal) protein isoform I-C

For Research Use Only. Not for use in diagnostic procedures.

Chromosome: 10; NC_000076.6 (120361275..120476935, complement). Location: 10 D2; 10 67.94 cM

Store all reagents at 2-8 degree C

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.

Small volumes of HMGA2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9324088 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the High mobility group protein HMGI-C (HMGA2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing HMGA2. The ELISA analytical biochemical technique of the MBS9324088 kit is based on HMGA2 antibody-HMGA2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect HMGA2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, HMGA2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

11,819 Da

high mobility group AT-hook 2

high mobility group protein HMGI-C; high mobility group AT-hook protein 2; high mobility group protein I, isoform C

High mobility group protein HMGI-C

Hmgic  [Similar Products]

HMGA2_MOUSE

HMGA2: Functions as a transcriptional regulator. Functions in cell cycle regulation through CCNA2. Plays an important role in chromosome condensation during the meiotic G2/M transition of spermatocytes. Interacts with E4F1. Interacts with NEK2. Belongs to the HMGA family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding; Oncoprotein

Cellular Component: nuclear chromosome; nucleus; chromatin

Molecular Function: protein binding; DNA-(apurinic or apyrimidinic site) lyase activity; enzyme binding; DNA binding; AT DNA binding

Biological Process: transcription from RNA polymerase II promoter; somatic stem cell maintenance; cell proliferation in forebrain; negative regulation of transcription from RNA polymerase II promoter; positive regulation of multicellular organism growth; signal transduction; regulation of growth hormone secretion; regulation of transcription, DNA-dependent; meiotic cell cycle; base-excision repair; regulation of growth; positive regulation of cell proliferation; mitosis; negative regulation of steroid hormone receptor signaling pathway; transcription, DNA-dependent; adrenal gland development; male gonad development; cell cycle; DNA catabolic process, endonucleolytic; chromosome condensation; cell proliferation; cell division; pituitary gland development; negative regulation of astrocyte differentiation; positive regulation of transcription from RNA polymerase II promoter; spermatogenesis; positive regulation of transcription factor activity; negative regulation of JAK-STAT cascade

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