Full Product Name
AAGAB Antibody - C-terminal region
Product Gene Name
anti-AAGAB antibody
[Similar Products]
Product Synonym Gene Name
AAGAB;[Similar Products]
Antibody/Peptide Pairs
AAGAB peptide (MBS3244257) is used for blocking the activity of AAGAB antibody (MBS3219371)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Synthetic peptide located within the following region: LLNSLTGTNH SIGSADPCHP EQPHLPAADS TESLSDHRGG ASNTTDAQVD
3D Structure
ModBase 3D Structure for Q6PD74
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human AAGAB
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-AAGAB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-AAGAB antibody
This is a rabbit polyclonal antibody against AAGAB. It was validated on Western Blot
Target Description: The protein encoded by this gene interacts with the gamma-adaptin and alpha-adaptin subunits of complexes involved in clathrin-coated vesicle trafficking. Mutations in this gene are associated with type I punctate palmoplantar keratoderma. Alternatively spliced transcript variants have been found for this gene.
Product Categories/Family for anti-AAGAB antibody
Polyclonal; Membrane & Traffic;
Applications Tested/Suitable for anti-AAGAB antibody
Western Blot (WB)
Western Blot (WB) of anti-AAGAB antibody
Host: Rabbit
Target Name: AAGAB
Sample Type: PANC1 Whole Cell lysates
Antibody Dilution: 1.0ug/ml
NCBI/Uniprot data below describe general gene information for AAGAB. It may not necessarily be applicable to this product.
NCBI Accession #
NP_078942
[Other Products]
NCBI GenBank Nucleotide #
NM_024666.4
[Other Products]
UniProt Primary Accession #
Q6PD74
[Other Products]
UniProt Related Accession #
Q6PD74[Other Products]
NCBI Official Full Name
alpha- and gamma-adaptin-binding protein p34 isoform 1
NCBI Official Synonym Full Names
alpha and gamma adaptin binding protein
NCBI Official Symbol
AAGAB [Similar Products]
NCBI Official Synonym Symbols
p34; KPPP1; PPKP1; PPKP1A
[Similar Products]
NCBI Protein Information
alpha- and gamma-adaptin-binding protein p34
UniProt Protein Name
Alpha- and gamma-adaptin-binding protein p34
Protein Family
Alpha- and gamma-adaptin-binding protein
UniProt Gene Name
AAGAB [Similar Products]
UniProt Entry Name
AAGAB_HUMAN
NCBI Summary for AAGAB
The protein encoded by this gene interacts with the gamma-adaptin and alpha-adaptin subunits of complexes involved in clathrin-coated vesicle trafficking. Mutations in this gene are associated with type I punctate palmoplantar keratoderma. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2012]
UniProt Comments for AAGAB
AAGAB: May play a role in membrane traffic.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: 15q23
Cellular Component: nucleoplasm; cytoplasm; cytosol
Biological Process: protein transport
Disease: Palmoplantar Keratoderma, Punctate Type Ia
Research Articles on AAGAB
1. Identical AAGAB genotypes presented a very broad interfamilial and intrafamilial variability of phenotypes in punctate palmoplantar keratoderma type 1 (Buschke-Fischer-Brauer syndrome).
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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